:ymphatics Flashcards
2 central lymphatic tissues
Bone marrow
Thymus
Secondary Lymph tissues
MALT, Lymph nodes, spleen
fate of B-cells
plasma cells or memory cells
fate to T cells
cell mediated immune response or memory cells
2 types of APC in lymphoid tissue
Macrophages, Dendritic cells
Location of non-encapuslated lymphatic tissue
GI, respiratory, urinary tract
presence of these in thymus indicate a problem
lymphatic nodules
non encapsulated tissue in illium
Peyer’s patches
function of non-encapsulated lymphatic tissues
trapping of antigen, lymphocyte production, destruction of antigen
location of lymph node where afferent vessels are not present
hilum
3 divisions of cortex
superificial, mid-cortex and deep cortex
primary location of T-Cells in lymph node
deep cortex
HEV
high endothelial venoule
functions of lymph node
lymph filiter, lymphocyte production, antibody production
cell origin of thymus
endoderm
Horomone of thymus do this to T-cells
promote differentiaion and induce formation of T-cell surface markers
mature T-cells exit the Thymus from this region through this venoule
Inner region, post capillary venoule
Cell is definitive for the thymus
Hassall’s corpuscles
vascular supply to thymus
internal thoracic and inferior thyroid arteries
blood thymus barriers prevent these from entering the thymus
antigens
The thymus and spleen do not have these types of vessels that the lymph nodes have
afferent lymphatic vessels
Organ with the thickest capsule
spleen
major component of white pulp of spleen
Pariarterial lymphatic sheaths (PALS)
elongated and narrow endothelial cells, like a barrel in spleen
sinusoids
most efficient APC
dendritic cell
2 functions of spleen
immune - activation and proliferation of B and T lymphocytes - hemopoietic - remove damaged platelets, store blood
