HIV Flashcards
Which drugs block HIV protease and prevent virion assembly?
Atazanir
Ritonavir
Darunavir
Name the capsid protein and which gene it is coded from?
p24
gag
What protein writes HIV mRNA and host RNA
Host RNA pol II
This enzyme writes HIV DNA into the host DNA
integrase
GP 120 on HIV binds with which host cell receptor?
CD4
2 band of these proteins are required for a Western Blot confirmation of HIV infection?
gp41, gp120 or p24
HIV-1 is a reserve transcript and performs this task?
RNA dependent DNA polymerase
When is a virus considered a pro-virus?
When its genome is written in the host DNA
Tat is a TF that promotes what type of RNA? What TF are written from spliced RNA?
spliced RNA
Tat, Rev, and Nef
What 3 proteins are written from unspliced RNA?
Env
Gag
Pol
What two chemokine receptors bind to gp41?
CCR5
CXCR4
What are some common opportunistic infections seen in patients with HIV?
Kaposi Sarcoma CMV Candida Cryptococcus Pneumocystis
When a T cell count falls below this level a patient is considered to have AIDS
200
How are HIV patients monitored?
CD4+ T cell enumeration with flow cytometry
What is the goal of therapy for patients with HIV?
Reduce the level of circulating virus