Immunology Flashcards

1
Q

List components of innate immune system.

A

Physical barriers, phagocytes, complement, interferon

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2
Q

What type of macrophage is found in the liver?

A

Kupfer cells

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3
Q

What PAMP does the TLR3 PRR bind?

A

Viral double stranded RNA

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4
Q

What happens if the innate immune system is evaded?

A

get sick and/or acquired immune system takes over

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5
Q

Name the interferon released by infected cells?

A

IFN alpha and beta

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6
Q

Name a type of cytokine that attracts immune cells to inflamed tissue?

A

chemokine

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7
Q

All leukocytes are identified by this molecule?

A

cluster of differentiation (CD) 45

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8
Q

What cell initiates adaptive immunity?

A

phagocytes

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9
Q

Compare the response of the adaptive immune system from first time to second time exposure?

A

first exposure response takes 7-10 days

the second response faster and stronger

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10
Q

What is the difference between active and passive immunity?

A

active- exposure to antibody or vaccine

passive- immunoglobulin from mother to baby or transfusion

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11
Q

What are two ways that complement is activated?

A

pathogen -innate

antibody- adaptive

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12
Q

What two types of cells do B cells differentiate into?

A

plasma cells and memory B cells

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13
Q

What is unique about NKCs?

A

NKCs kill cells that do not have an MHCI complex on them

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14
Q

Where do mast cells reside?

A

skin, mucosa, conjunctiva, mouth, nose

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15
Q

What cytokine promotes diapedesis of PMNs?

A

IL-8

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16
Q

What receptors are found on mast cells?

A

Fc for IgE

17
Q

What are the factors that promote differentiation of platelets?

A

GM-CSF, IL-3, IL-6 (colony stimulating factor)