Benign Leukocytosis Flashcards
If you see Basophillia think this?
CML
2 types of Neutrophilia?
Mature and immature
Causes of mature neutrophilia
Bacterial Infection
Inflammation
Stress of hormones
Causes of immature neutrophilia
Bacterial infection
Inflammation
Severe anemia
Mass in the bone marrow
3 forms of immature neutrophilia
Left Shift
Leukomoid reaction
Leukoerthyroblastotic reaction
In which type of Neutrophilia would you see toxic changes?
Mature bacterial infections only?
Name some examples of toxic changes in Neutrophilia?
Toxic granulation
Dohle bodies
cytoplasmic vacuolization (worst)
What is a leukemoid reaction?
Increased WBC count seen with infection, nonmalignant.
What is a leukoerythoblastotic reaction?
Increased immature WBC count w/ nucleated RBC
May be benign or malignant
Somes cause of eosinophillia
Drugs, Asthma, Skin diseases, parasites
This type of leukocytosis is always bengin
Eosinophillia
Which leukocytosis is always malignant
Basophillia which is a sign of CML
Test which distinguishes CLL from benign lymphocytosis?
Immunophenotyping
Name some causes of monocytosis?
Infection, autoimmune, malignant
definition of benign leukcytoses
elevated values of lymphocytes. usually meurtrophils or lymphocytes
benign cause of high WBC
demargination
1 cause of mature neutrophilia
bacterial infection
define left shift
more immature cells hanging around
This count varies as you age, and has the largest range in infants
Lymphocytes
ratio of T cells, B cells and NK cells
80, 15, 5
This leukemia is never found in kids
CLL
Eosinophilia is associated with these conditions
Drugs, asthma, skin disease, parasites
