Blood Flashcards
Cells of blood
Ertyhrocytes, Leukocytes, Platelets, hemoconia, Chylomicrons
Difference between plasma and serum
plasma clots, serum lacks firbringoen
diameter of RBC
7.7 micron
3 cytoskeleton elements of RBC
spectrin, ankyrin, actin
stack of red blood cells
rouleaux
diameter platelet
1/2 RBC - 2-4 microns
Granulocytic leukocytes
neutrophils, Eosinophils, Basophils
Agranulocytic leukocytes
lymphocytes, monocytes
all leukocytes contain these granules of lyzomes
azurophilic
multi lobe leukocyte
neutrophil
first line of cellular defense
neutrophil
bi-lobed nucleus
eosinophils
eosinohils use arginine to combat these
parasites/protazoas
eosinophil locations
ct of digestive and resp. tract
known for parasitic destruction these cells also migrate to sites of allergic reactions
eosinophils
basophilic granules contain contain these important cells
histamine, heparin, peroxidase, chemotactic factors
basophils increase in these situations
leukemiz, chickenpox, sinus inflammation
basophil have Fc fragment for this Ig
IgE
3 classes of lymphocytes
B, T and Null (NK)
B-lymphocytes fate (2)
plasma and memory
majority of lymphocytes are of this type
T-lymphocytes
3 subsets of T cells
Cytoxic T cells, T helper cells, T suppressor cells
kidney bean nucleus cell
monocyte
monocytes become these cells in the ct
macrophages
find these cells in blood after fatty meal
chylomicrons
blood debris
hemoconia
granulocytes in lymph is significant for what?
pathological problem
Tissue produces most blood cell types, location
Myeloid, medullary cavity of bones
Tissue responsible for immune defenses of body, location
Lymphatic, thymus, lumph nodes, spleed, lymph nodules
hematiopoetic tissue is derived from this
mesenchyme
first hemopoiesis takes place here
yolk sac
major blood formation in fetus
liver
location of red marrow
skull, ribs, sternum, vertebral bodies, cancellous bone, long/short bones, iliac crest
component of myeloid tissue
stroma, sinusoid, blood cells
Holes in these structures allow cells to move from stroma to capillaries
sinusoids
regulating factor that limits blood cells to a certain fate
poietins (erythropoietin)
EPO is produced here
kidney, liver
stage at which nucleus is pushed out of RBC
Orthochromatiophilici erythroblast –> reticulocyte
Myeloblasts become larger with more granulocytes and are called these cells
pro-myelocyte
first cell in granulocyte progression that is not mitotic
metamyelocyte
granule cells with dented nucleus
metamyelocyte
granular series cell that does not contain granules
blast
platelets are formed from these cells
Megakaryocytes
Normal value for RBC
M - 4.3-5.7 trillion/L F - 3.9 -5 trillion/L
Normal range for WBC
3.5-10.5 billion/Liter
Normal range for eosiniophils
0-7% of PMNs
Approximately how long does granulopoesis take?
14 days
Normal range for platelets
120-450 billion/L
What cells are contained in the bone marrow stroma
Macrophages, fibroblasts, fat storing cells, osteogenic factors, endeothelial
Hypoxia results in the release of what poietin?
EPO