Y4 Epilepsy Flashcards
1
Q
state some diagnostic signs that would suggest seizure over syncope?
A
Aura Specific trigger: e.g. flashing lights Lateral tongue biting (> incontinence) Typical movements: e.g. tonic-clonic Cyanosis Post-ictal phase
2
Q
should epilepsy be diagnosed after one seizure ?
A
no
3
Q
what are some SEs of lamotrigine?
A
Diplopia, blurred vision
skin rash - may develop into SJS
4
Q
what are some SEs of valproate ?
A
Appetite ↑ Liver failure: monitor LFTs over 1st 6mo Pancreatitis Reversible hair loss Oedema Ataxia Teratogenicity, Tremor, Thrombocytopaenia Encephalopathy: due to ↑ ammonia
5
Q
what are SEs of carbamazepine ?
A
Leukopenia
Skin reactions
Diplopia, blurred vision
SIADH → hyponatraemia
6
Q
what are the SEs of phenytoin?
A
Gingival hypertrophy Hirsutism Cerebellar syn. - Ataxia - Nystagmus - Dysarthria Peripheral sensory neuropathy Diplopia Tremor
7
Q
what investigations should be done for a first seizure?
A
Basic bloods: FBC, U+Es, glucose Se ↑ Prl 10min after fit (relative to baseline) Se AED levels Urine toxicology ECG
8
Q
what are two contraindications of phenytoin ?
A
CI: bradycardia or heart block
