Wk3 Male Repor Histo Flashcards
Forms the lobules and mediastinum of testes:
Tunica albuginea
Sac surrounding anterior and lateral parts of testes:
Tunica vaginalis
Lobules of testes contain:
seminiferous tubules
Location of spermatogenesis:
seminiferous tubules
Four cell stages of spermatogenesis in seminiferous tubules:
- Spermatogonium (outermost)
- Primary spermatocytes
- secondary spermatocytes (rarely visualized)
- early spermatids
**slide 16
Ploidy of spermatogonia:
diploid
“Reserve” stem cells for spermatogenesis:
Dark type A spermatogonia
“renewing” stem cells for spermatogenesis:
Pale type A spermatogonia
differentiating progenitors of spermatogenesis:
Type B spermatogonia
Largest germ cell
enter Meiosis I
distinct nuclear profiles
Primary spermatocytes
germ cells that are rarely seen
rapidly enter meiosis II
Secondary spermatocytes
Review slides…
25-27
Pillar like cells that extend from the basement membrane to the lumen of the seminiferous tubule:
Sertoli cells
Blood-testes barrier formed by:
Sertoli cells
Cells with FSH receptors:***
Sertoli cells
Cells that produce androgen binding protein
Sertoli cells
Testosterone producing cells:
Leydig
**extensive smooth ER
LH act on _______ cells.
Leydig
Cells that produce inhibin:
Sertoli
Cryptorchidism effect on androgen production:
Why?
None
Leydig’s are not temperature sensitive
What does inhibin do?
Sertoli cells –> negative feedback on pituitary –> inhibits FSH release
**inhibits FSH release
What is the negative feedback mechanism on both the hypothalamus and the pituitary:
testosterone from Leydigs
Path for sperm after leaving the seminiferous tubule:
Straight tubule –>
Rete testis –>
Efferent ductules –>
Ductus epidiymis –>
Vas deferens –>
Ampulla of vas deferens –>
Ejaculatory duct –>
Urethra
**slide 68
Epithilium is characterized by Tall/Short cells:
Efferent ductules