Wk3 Female Repro Histo Flashcards
Ovarian cortex layer immediately beneath germinal epithelium:
Tunica albuginia
Embryological origin of primordial germ cells:
Yolk sac
When does the first meiotic division of oocyte occur?
just prior to ovulation
When does second meiotic division of oocyte occur?
at fertilization
Follicular development summary…
slide 23
5 phases of follicular development:
- Primordial follicle
- Unilaminar primary follicle
- Multilaminar primay follicle
- Secondary follicle (distinguished by presence of antrum)
- Graafian follicle (antrum is now continuous)
Single layer of flattened cells surrounding oocyte in primordial follicle:
Follicular cells
location of FSH receptors:
Follicular cells
Follicular cells become stratified columnar to form ________ in _________ follicles.
granulosa cells
primary follicles
Gel like layer surrounding oocyte in primary follicles – eosinophillic
zona pellucida
Forms just outside granulosa layer:
Theca interna
Antrum formation signifies which follicles:
Secondary
Produces androgens
Theca interna
granulosa cells surrounding oocyte and zona pellucida:
corona radiata
What signals final maturation of follicles:
LH –> first meiotic division, polar body formed
What triggers ovulation:
LH surge
Cells with LH receptors
Granulosa
theca
Two roles of FSH in folliculogenesis:
- stimulate granulosa cell growth and estrogen synthesis
2. (later) stimulates formation of LH receptors
Two roles of LH in folliculogenesis:
- stimulates thecal cell growth and androgen production
2. stimulates progesterone production in granulosa cells
Where are androgens converted to estrogen?
Granulosa cells
Temporary glandular structure from remnants of ruptured follicle after ovulation:
Corpus luteum
What do granulosa cells become in Corpus lutem?
granulosa lutein cells
produce estrogen and progesterone
What do theca interna cells become in Corpus luteum:
theca lutein cells
produce estrogen and progesterone
If no fertilization, what does Corpus luteum become?
corpora albicans