Wk2 Trachte Drugs and receptors Flashcards

1
Q

GHRH receptor?

A

Gs

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2
Q

Dopamine receptor:

A

Gi

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3
Q

TRH receptor:

A

Gq

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4
Q

CRH receptor:

A

Gs

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5
Q

GH receptor:

A

JAK

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6
Q

TSH receptor:

A

Gs

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7
Q

ACTH receptor:

A

Gs

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8
Q

IGF-1 receptor:

A

Tyrosine Kinase

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9
Q

TH receptor:

A

transcription (intracellular)

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10
Q

Cortisol receptor:

A

transcription (intracellular)

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11
Q

Insulin receptor:

A

Tyrosine kinase

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12
Q

Glucagon receptor:

A

Gs-alpha

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13
Q

Bromocriptine

A

D2 agonist, inhibits prolactin

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14
Q

Cabergoline

A

D2 agonist, inhibits prolactin

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15
Q

Somatotropin

A

GH analog

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16
Q

Mecasermin

A

IGF-1 analog

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17
Q

Sermorelen

A

GHRH analog

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18
Q

Pegvimostat

A

GH receptor antagonist

19
Q

Levothyroxine

A

T4

20
Q

Lyothyronone

A

T3

21
Q

Propylthiouracil

A

Thyroglobulin peroxidase inhibitor

22
Q

Methamizole

A

Thyroxin peroxidase inhibitor

23
Q

Cortisol

A

glucocorticoid

24
Q

Prednisolone

A

glucocorticoid

25
Q

Betamethasone

A

glucocorticoid

26
Q

Triamcinolone

A

glucocorticoid

27
Q

Dexamethasone

A

glucocorticoid

28
Q

Fludricortisone

A

mineralocorticoid

29
Q

Desoxycorticosterone

A

glucocorticoid

30
Q

Beclomethasone

A

glucocorticoid

31
Q

Fluticasone

A

glucocorticoid

32
Q

Mefipristone

A

glucocorticoid receptor antagonist

33
Q

Spironolactone

A

mineralocorticoid receptor antagonist

34
Q

Metformin

A

inhibits gluconeogenesis

35
Q

Glimeperide

A

insulin secretagogue, closes K+ channel

36
Q

Insulin

A

hypoglycemic effect

37
Q

Exenitide

A

GLP-1 analogue

insulin secretagogue, increases cAMP via AC

38
Q

Sitagliptin

A

inhibits destruction of GLP-1/GIP by DDP-IV

indirect insulin secretagogue

39
Q

Repaglinide

A

insulin secretagogue, closes K+ channel

40
Q

Nataglinide

A

insulin secretagogue, closes K+ channel

41
Q

Acarbose

A

a-glucosidase inhibitor, decreases glucose uptake

42
Q

Pramlinitide

A

amylin analog, inhibits glucagon release

43
Q

Rosiglitazone

A

PPAR agonist, enhances insulin effect

44
Q

Pioglitazone

A

PPAR agonist, enhances insulin effect