Wk1 Pituitary Path Flashcards
Basophils secrete:
FSH
LH
ACTH
TSH
B-F-L-A-T
Acidophils secrete:
GH
PL (prolactin)
Posterior pituitary secretes:
Oxytocin
ADH
Definition of hyperpituitarism:
too much anterior pituitary hormones
Most common cause of hyperpituitarism:
pituitary adenoma
Most common PE finding in pituitary adenoma:
visual deficits
temporal hemianopsia
Most common hormone produced by pituitary adenoma:
prolactin
Least common hormone produced by pituitary adenoma:
TSH
Tx for prolactinoma:
D2 antagonists
Two outcomes of GH adenoma:
What’s the difference?
Gigantism – pre-puberty
Acromegaly – post puberty (Andre the Giant)
Lab findings in GH adenoma:
increased IGF-I
GH unresponsive to glucose
“Explosion” in ACTH adenoma after surgical resection of adrenals:
Nelson syndrome
Cause of central diabetes insipidus:
decreased ADH production
Clinical manifestations of central diabetes insipidus:
pee dilute urine (collecting tubules don’t have AHD to take up water)
increased serum osmolality (can’t get water in to dilute)
Clinical manifestation of SIADH:
blood becomes hypotonic