Week 8: Adrenal gland disorders

Question 1

the adrenal gland is triggered under _____

Answer 1

stress

Question 2

the ____ releases corticotropin releasing hormone (CRH), and _____ releases ACTH. ACTH travels to ___ ___. The ACTH will stimulate the release of _____, ____ and steroids using the ____ ____ system

Answer 2

hypothalmus 
anterior pituitary 
adrenal gland 
glucocorticoiods
mineralcorticoids
negative feedback

Question 3

in cushing disease there is ____ _____ in the body. this results in an increased _____, decrease in the ____ and ___ response.

Answer 3

excess glucocorticoids
metabolism
immune and inflamatory

Question 4

____ can result from adrenal cortex or prednisone

Answer 4

cushing

Question 5

clinical manifestations of cushings

Answer 5

obsity of trunk, moon face, upper back fat pad
wasting of extermities 
glucose intolerance- high blood sugar
prone to infection- suppression of inflamation/immune system
impaired stress response
behavioral response 
hypokalemia- due to increased urination
renal caliculi

Question 6

diagnosing cushings

Answer 6

24 hours urine collection

image studies

Question 7

treatment of cushings

Answer 7

remove tumors by radiation or chemo
gradually taper off glucocoritoid medication-
cant stop immediately because brain sees we have enough (even if articital). the body cant ramp back up quickly

Question 8

addisons disease is when there is ____ _____

Answer 8

deficient glucocorticoids

Question 9

____ ____ is an autoimmune destruction of the adrenal _____. there will be _____ ACTH and ___ glucocorticoids, mineralocorticods and androgen

Answer 9

addisons diasease
cortex
high ACTH
low gluco, minero, androgen