Week 6: COPD Flashcards
In emphysema we are having issues at the a____ ____ junction, so we are going to have an issue with _____
Alveolar- capillary
Diffusion
_____ of the gas exchange airways and difficulty with ____ due to decreased airway patency. There can also be an ____ issue which is why it’s classified under c__ ___ ___ ____
Enlargement
Expiration
Obstruction
Chronic obstructive pulmonary disorders
The _____ have become ____ in emphysema and fibrotic so they don’t release ___
CAPILLARIES
Thickened
Co2
____ is the number one reason people get emphysema
Smoking
A genetic deficiency of a___ _ _______ can lead to an early form of emphysema that is not ___ related
Alpha 1 antitrypsin
Smoking
A__ ___ occurs with emphysema. We are getting ___ in but are having trouble getting ___ out
Air trapping
O2
Co2
The breakdown of the ___ ___ leads to a loss of surface area for ___ ___. This will lead to a loss of ____ capillaries and mess up the ____ _____ ratio
Alveolar wall
Gas exchange
Pulmonary
Ventilation: perfusion
The ____ of some capillaries can lead to ___ airways, weakened walls, and interfere with the p___ ___ airflow
Fibrosis
Narrowed
Passive expiratory
As condition progresses person will start to trap air in the ____ and eventually increase their t____ ___ ___, leading to inflation and altered chest anatomy
Alveoli
Total residual volume
Barrel chest ap:t ratio
Is 1:1
Normal chest ap: t ratio
1:2
Person with emphysema may have f___ of ___ in respiratory position, b___ ___, and f___ ____
Fixation of ribs
Barrel chest
Flattened diaphragm
_____ occurs when the damaged walls of the aveoli collapse and join together forming large air spaces and then rupture
Pneumothorax
In advanced emphysema there is h___ and there is an increase in that h___ drive. The chronic levels of __ are going to shut off those chemoreceptors looking at ___ as our respiratory drive and turn on our ___ ___ receptors
Hypercapnea Hypoxic drive Co2 Co2 Peripheral o2 receptors
Patients with advanced emphysema are more prone to i___ due to compromised immune function
Infection
emphysema: Issues with p___ and v___ and lack of ___ can result in ___ ____. Leading to ___ ___ ____ and eventually ___ ___ ___ ___
Perfusion Ventilation O2 Pulmonary HTN Right ventricular hypertrophy Right sided heart failure
Cor pulmonary
R ventricular hypertrophy due to work against pulmonary HTN
In emphysema ___will begin to occur on _____. Eventually this will occur __ ___
Dyspnea
Exertion
At rest
emphysema: have ______ with prolonged ____ phase because they are trying to ____ off that ____
Hyperventilation
Expiratory
Blow
Co2
emphysema: called ___ ____ because they are _____. It is not necessarily an ___ issue so they will be more _____
Pink puffers
Hyperventilating
O2
Pink
Patient with emphysema will have ____ _____, and possibly ____ in late stages
Anorexia
Fatigue
Cynosis