Vulvar and Vaginal Neoplasms Flashcards

1
Q

Vulvar neoplasms are usually what type?

A

Squamous Cell Carcinomas

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2
Q

When do Vulvar neoplasms usually occur?

A

Post-menopause

– > 65 yo

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3
Q

What is the most frequently reported symptom of Vulvar Neoplasms?

A

Long history of chronic vulvar pruritus

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4
Q

What is the most frequently reported symptom of Vulvar neoplasms?

A

Long history of chronic vulvar pruritus

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5
Q

VIN

A

Vulvar Intraepithelial neoplasia — precursor lesion

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6
Q

Classic VIN

A

Associated with HPV 16, smoking and immunocompromised

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7
Q

Differentiated VIN

A

Associated with vulvar dermatologic conditions

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8
Q

What is the treatment for VIN III?

A

Local surgical excision – 5 mm

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9
Q

What is the treatment for small VIN III lesions?

A

Laser therapy

- take biopsies too

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10
Q

Paget’s disease is also a preinvasive condition. What does it look like?

A

Red with white plaque lesions, itching and tenderness

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11
Q

Squamous Cell Vulvar Carcinoma is usually where and whats the symptom?

A

Labia majora

= Itch

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12
Q

What are 2 treatment options for Squamous Cell Vulvar Carcinoma?

A
  • Radical vulvectomy and regional lymphadenectomy

- Tumor excision, inguinal node dissection, chemo/radiation

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13
Q

Verrucous Carcinoma can also occur on the vulva. What is it?

A

Squamous Cell Carcinoma variant

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14
Q

How does Verrucous Carcinoma look on the vulva?

A

Cauliflower lesion

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15
Q

What treatment is contraindicated with Verrucous Carcinomas and why?

A

Radiation

-> anaplastic transformation

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16
Q

Bartholin’s gland carcinoma can also occur. Symptom?

A

Painless mass

17
Q

Will a patient with a Bartholin’s gland carcinoma have a history of Bartholin gland issues?

A

NO

18
Q

What is the treatment for Bartholin’s Gland Carcinoma?

A

Radical vulvectomy, bilateral lymphadenectomy, radiation

19
Q

Is recurrence common with Bartholin’s Gland Carcinoma?

A

Yes

20
Q

VAIN

A

Vaginal Intraepithelial Neoplasia – precursor lesion

21
Q

What is VAIN associated with?

A

HPV

22
Q

Symptom of VAIN?

A

Asymptomatic

23
Q

Vaginal Carcinoma is usually what type?

A

Squamous Cell Carcinoma

24
Q

What are the symptoms of Vaginal Squamous Cell Carcinoma?

A

Abnormal vaginal discharge/bleeding and hematuria

25
Q

What type of biopsy is needed with Vaginal Carcinoma?

A

Punch biopsy

26
Q

The treatment for Vaginal Squamous Cell Carcinoma is radiation. What specific instructions are included for the lower and upper vagina?

A

Lower - include groin nodes with radiation

Upper - surgery

27
Q

What vaginal tumor occurs in young girls?

A

Sarcoma Botryoides (embryonal rhabdomyosarcoma)

28
Q

In what age group do Sarcoma Botryoides occur?

A

YOUNG girls

29
Q

What does a Sarcoma Botryoides look like?

A

Grape like mass