Vulvar and Vaginal Neoplasms Flashcards
Vulvar neoplasms are usually what type?
Squamous Cell Carcinomas
When do Vulvar neoplasms usually occur?
Post-menopause
– > 65 yo
What is the most frequently reported symptom of Vulvar Neoplasms?
Long history of chronic vulvar pruritus
What is the most frequently reported symptom of Vulvar neoplasms?
Long history of chronic vulvar pruritus
VIN
Vulvar Intraepithelial neoplasia — precursor lesion
Classic VIN
Associated with HPV 16, smoking and immunocompromised
Differentiated VIN
Associated with vulvar dermatologic conditions
What is the treatment for VIN III?
Local surgical excision – 5 mm
What is the treatment for small VIN III lesions?
Laser therapy
- take biopsies too
Paget’s disease is also a preinvasive condition. What does it look like?
Red with white plaque lesions, itching and tenderness
Squamous Cell Vulvar Carcinoma is usually where and whats the symptom?
Labia majora
= Itch
What are 2 treatment options for Squamous Cell Vulvar Carcinoma?
- Radical vulvectomy and regional lymphadenectomy
- Tumor excision, inguinal node dissection, chemo/radiation
Verrucous Carcinoma can also occur on the vulva. What is it?
Squamous Cell Carcinoma variant
How does Verrucous Carcinoma look on the vulva?
Cauliflower lesion
What treatment is contraindicated with Verrucous Carcinomas and why?
Radiation
-> anaplastic transformation