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ENRP > Vagina + Cervix > Flashcards

Vagina + Cervix Flashcards

1
Q

Cysts occur in reproductive aged women. Can you have a Mullerian cyst that is from the Mullerian (paramesonephric) duct?

A

Yes

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2
Q

What causes a Gartner Duct Cyst?

A

Wolffian (mesonephric) duct remnants

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3
Q

What are 2 cysts that can occur in the vagina and where usually?

A

Anterior lateral walls and possibly protruding from orifice

  1. Gartner Duct Cyst
  2. Mullerian Cyst
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4
Q

What are the symptoms of Vaginal cysts?

A

Asymptomatic or pain with sex

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5
Q

If women are given DES (diethylstilbestrol) while they are pregnant, what may their daughter develop?

A

Clear cell adenocarcinoma

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6
Q

If a woman develops a clear cell adenocarcinoma, what was her mom given while she was pregnant with her?

A

DES

diethylstilbestrol

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7
Q

What vaginal malignancy affects infants and young girls (<5)?

A

Vaginal Embyronal Rhabdomyosarcoma

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8
Q

How does a Vaginal Embyronal Rhabdomyosarcoma look?

A

Protruding grape-like mass

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9
Q

What cells are present with Vaginal Embyronal Rhabdomyosarcomas? Is death possible?

A

Embryonal Rhabdomyoblasts

– invasion of structures can cause death

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10
Q

What does Vaginal Squamous cell carcinoma start with?

A 
Precursor VAIN
(vaginal intraepithelial neoplasia)
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11
Q

What HPV strands cause Vaginal SCC?

A

HPV 16/18

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12
Q

Vaginal SCC of the lower 2/3 of the vagina spreads to what lymph nodes?

A

Inguinal/femoral

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13
Q

Vaginal SCC of the upper 1/3 of the vagina spreads to what lymph nodes?

A

Iliac

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14
Q

What causes almost ALL cervical and vaginal carcinomas?

A

HPV 16 or 18

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15
Q

What causes almost ALL cervical and vaginal carcinomas?

A

HPV 16 or 18

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16
Q

HPV 16/18 has a predilection for what anatomic location?

A

Transformation zone of the cervix

17
Q

When HPV integrates into the genome, it creates E6 and E7. What are the 2 jobs of E6?

A
  • Increase Telomerase

- Degrade P53

18
Q

When HPV integrates into the genome it creates E6 and E7. What is the job of E7?

A
  • Inactivates P21 and RB to cause cellular proliferation
19
Q

With the cervix, what does LSIL and HSIL stand for and which has a 10% chance of becoming invasive SCC and has more dysplasia present?

A

LSIL = low grade squamous intraepithelial lesion
HSIL = high grade squamous intraepithelial lesion
** HSIL can become invasive SCC

20
Q

How do you screen for Cervical Dysplasia?

A

PAP test

21
Q

If a PAP test cannot determine the cells present with cervical dysplasia, what tests should be used and what do they do?

A

PCR assay or Hybrid capture

= Test fluid for high risk HPV (16/18)

22
Q

When should PAP tests start?

A

21 years old

23
Q

Pap test regulations for 21-29

A

Cytology every 3 years

24
Q

Pap test regulations for 30-65

A

Co-testing with high risk HPV molecular test every 5 years

if normal

25
Q

If a woman is not at high risk for cervical cancer, when can Pap tests stop?

A

65+

26
Q

If an Abnormal pap test results, what is another test that can be done?

A

Colposcopy with biopsy

27
Q

Colposcopy with biopsy can help to determine?

A

Cervical dysplasia

28
Q

What is applied to the cervix to help visualize it with a Colposcopy?

A

Acetic acid

29
Q

What color areas raise concern for dysplasia with a Colposcopy?

A

Acetowhite areas

+/- punctuation

30
Q

With a Colposcopy, what can be present that is a carcinoma concern?

A

Atypical vessels

31
Q

If HSIL is present in the cervix, what are 2 treatment options?

A

Cervical colonization - cut out

LEEP - loop electrosurgical excision

32
Q

What is the most common type of Cervical cancer?

A

Invasive Squamous Cell Carcinoma

33
Q

If a woman has a Cervical Adenocarcinoma, what preceded it?

A

AIS

adenocarcinoma in situ

34
Q

What is the average age for Cervical cancer?

A

45-50

35
Q

What can prevent Cervical Cancers in females and males?

A

VACCINATION - at 11/12 years old

36
Q

Endocervical polyps are benign. When are they commonly seen?

A

Reproductive years especially after 40

37
Q

What is the symptom with an Endocervical Polyp?

A

Spotting

38
Q

What is an endocervical polyp made of?

A

Benign glands and stroma

39
Q

What is the treatment for Endocervical Polyps (benign)?

A

Excision

ENRP (45 decks)

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