Puberty Flashcards
What defines puberty?
Development of secondary sexual characteristics AND
Acquisition of reproductive capability
Between what ages does puberty usually occur?
10-16
What 3 things can all determine the onset of puberty?
Genetics
Geography
Nutritional status – need to be above 106 lbs
When does a females lifetime peak of oocytes occur?
16-20 weeks mid gestation
Between what ages is the H-P-O axis suppressed?
4-10
What are the stages of Puberty?
Thelarche
Pubarche/Adrenarche
Maximal growth
Menarche
What are the stages of Puberty?
Thelarche
Pubarche/Adrenarche
Maximal growth
Menarche
Thelarche is? What does it require
Breast development
– requires estrogen
Describe the Tanner staging for Thelarche
1: Preadolescent
2: breast bud elevation as small mound
3: further enlargement of breast bud
4: projection of areola and papilla about the breast mound
5: areola regresses into breast contour – papilla projection only
Describe the Tanner staging for Thelarche
1: preadolescent
2: breast bud elevation as small mound
3: further enlargement of breast bud
4: projection of areola and papilla above breast mound
5: areola regresses into breast contour; only papilla projects
Pubarche/Adrenarche is? What does it require?
Pubic and axillary hair growth
– requires androgens
Describe the Tanner staging of Pubarche
1: preadolescent
2: sparse hair along labia
3: darker hair continues to spread
4: NOT on thighs
5: ON medial thighs
Describe the Tanner staging for Pubarche
1: preadolescent
2: sparse hair along labia
3: darker hair continues to spread
4: NOT on thighs
5: ON medial thighs
When does Maximal growth occur?
1 year before menses
What does Menarche require?
Pulsatile GnRH and normal HPO axis
What is Precocious Puberty?
Development of any sign of secondary characteristics
– usually before 8 (2.5 SD)
Development of any secondary sexual characteristics before 8 (2.5SD)?
Precocious Puberty
Heterosexual Precocious Puberty
Develop secondary sexual characteristics OPPOSITE expected
Isosexual Precocious Puberty
Develop secondary sexual characteristics that are expected
Precocious Puberty is usually idiopathic but you need to eliminate serious disease. Why?
Can lead to osseous maturation => SHORT stature
What are the 2 types of Isosexual Precocious Puberty?
- True
- Pseudoisosexual
What causes True Isosexual Precocious Puberty?
Premature activation of the HPO axis
How can you test if Isosexual Precocious Puberty is True?
Administer GnRH
=> will see LH elevation
If True Isosexual Precocious Puberty is due to a CNS disorder, what other symptom will be present and what should you get?
Neuro symptoms present
– > get MRI of head
