Puberty Flashcards

1
Q

What defines puberty?

A

Development of secondary sexual characteristics AND

Acquisition of reproductive capability

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2
Q

Between what ages does puberty usually occur?

A

10-16

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3
Q

What 3 things can all determine the onset of puberty?

A

Genetics
Geography
Nutritional status – need to be above 106 lbs

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4
Q

When does a females lifetime peak of oocytes occur?

A

16-20 weeks mid gestation

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5
Q

Between what ages is the H-P-O axis suppressed?

A

4-10

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6
Q

What are the stages of Puberty?

A

Thelarche
Pubarche/Adrenarche
Maximal growth
Menarche

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7
Q

What are the stages of Puberty?

A

Thelarche
Pubarche/Adrenarche
Maximal growth
Menarche

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8
Q

Thelarche is? What does it require

A

Breast development

– requires estrogen

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9
Q

Describe the Tanner staging for Thelarche

A

1: Preadolescent
2: breast bud elevation as small mound
3: further enlargement of breast bud
4: projection of areola and papilla about the breast mound
5: areola regresses into breast contour – papilla projection only

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10
Q

Describe the Tanner staging for Thelarche

A

1: preadolescent
2: breast bud elevation as small mound
3: further enlargement of breast bud
4: projection of areola and papilla above breast mound
5: areola regresses into breast contour; only papilla projects

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11
Q

Pubarche/Adrenarche is? What does it require?

A

Pubic and axillary hair growth

– requires androgens

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12
Q

Describe the Tanner staging of Pubarche

A

1: preadolescent
2: sparse hair along labia
3: darker hair continues to spread
4: NOT on thighs
5: ON medial thighs

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13
Q

Describe the Tanner staging for Pubarche

A

1: preadolescent
2: sparse hair along labia
3: darker hair continues to spread
4: NOT on thighs
5: ON medial thighs

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14
Q

When does Maximal growth occur?

A

1 year before menses

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15
Q

What does Menarche require?

A

Pulsatile GnRH and normal HPO axis

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16
Q

What is Precocious Puberty?

A

Development of any sign of secondary characteristics

– usually before 8 (2.5 SD)

17
Q

Development of any secondary sexual characteristics before 8 (2.5SD)?

A

Precocious Puberty

18
Q

Heterosexual Precocious Puberty

A

Develop secondary sexual characteristics OPPOSITE expected

19
Q

Isosexual Precocious Puberty

A

Develop secondary sexual characteristics that are expected

20
Q

Precocious Puberty is usually idiopathic but you need to eliminate serious disease. Why?

A

Can lead to osseous maturation => SHORT stature

21
Q

What are the 2 types of Isosexual Precocious Puberty?

A
  • True

- Pseudoisosexual

22
Q

What causes True Isosexual Precocious Puberty?

A

Premature activation of the HPO axis

23
Q

How can you test if Isosexual Precocious Puberty is True?

A

Administer GnRH

=> will see LH elevation

24
Q

If True Isosexual Precocious Puberty is due to a CNS disorder, what other symptom will be present and what should you get?

A

Neuro symptoms present

– > get MRI of head

25
Q

What is the treatment for True Isosexual Precocious Puberty?

A

GnRH AGONIST

– (-) release of LH and FSH

26
Q

What is the treatment for True Isosexual Precocious Puberty?

A

GnRH Agonist

27
Q

What causes Pseudoisosexual Precocious Puberty?

A

Estrogen exposure from elsewhere

– NO activation of the HPO axis

28
Q

What causes Pseudoisosexual Precocious Puberty?

A

Estrogen exposure from elsewhere

– NO activation of the HPO axis

29
Q

If Pseudoisosexual Precocious Puberty is due to McCune-Albright, what else will be present?

A

Cafe au lait spots

30
Q

If Pseudoisosexual Precocious Puberty is due to Peutz-Jeghars what else will be present?

A

GI polyps and Mucocutaneous Pigmentation

31
Q

List items that can define Delayed Puberty (4)

A
  • NO sec. sex characteristics by 13
  • NO thelarche by 14
  • NO menarche by 15
  • NO menses 5 years after onset of thelarche
32
Q

List items that can define Delayed Puberty (4)

A
  • NO secondary sexual characteristics by 13
  • NO thelarche by 14
  • NO menarche by 15
  • NO menses 5 years after onset of thelarche