Part 2 Gyn. Infections

Question 1

What are the symptoms of Cervicitis?

Answer 1

Red, inflamed cervix with purulent discharge
Bleeding
Vaginal irritation

Question 2

What are the symptoms of Cervicitis?

Answer 2

Red, inflamed cervix with purulent discharge
Bleeding
Vaginal irritation

Question 3

What are the 3 most common organisms that cause Cervicitis?

Answer 3

Neisseria Gonorrhea
Chlamydia Trachomatis
Mycoplasma Genitalium

Question 4

What are the 3 most common organisms that cause Cervicitis?

Answer 4

N. Gonorrhea
Chlamydia
Mycoplasma Genitalium

Question 5

Gonorrhea and Chlamydia are both Gram (-) Intracellular bacteria. Which one grows on Thayer-Martin Chocolate Agar?

Answer 5

Neisseria Gonorrhea

Question 6

What is the virulence factor that N. Gonorrhea uses for adherence?

Answer 6

Pili

Question 7

What are the 2 virulence factors that N. Gonorrhea uses to prevent immune response?

Answer 7

IgA

OPA

Question 8

How does Chlamydia Trachomatis appear on gram stain?

Answer 8

DOES NOT APPEAR

– too small

Question 9

What is the IM treatment for Cervicitis?

Answer 9

Ceftriaxone (3rd gen)

Question 10

What is the oral treatment for Cervicitis?

Answer 10

Azithromycin

Question 11

What is the MOA for the IM treatment of Cervicitis?

Answer 11

Ceftriaxone = (-) cell wall synthesis and beta lactams

Question 12

What is the MOA for the oral treatment of cervicitis?

Answer 12

Azithromycin = (-) 50s protein synthesis

Question 13

Doxycycline can also treat Cervicitis. What is its MOA and pregnancy risk category?

Answer 13

(-) 30s protein synthesis

– Category D

Question 14

3 possible drugs to treat Cervicitis?

Answer 14

Ceftriaxone
Azithromycin
Doxycycline

Question 15

3 possible drugs to treat Cervicitis?

Answer 15

Ceftriaxone
Azithromycin
Doxycycline

Question 16

PID can present similarly to cervicitis but it has what extra symptoms?

Answer 16

Fever

Cervical motion tenderness

Question 17

PID has symptoms that involve cervicitis and?

Answer 17

Cervical motion tenderness

Fever

Question 18

What are the 2 most common causes of PID?

Answer 18

Gonorrhea

Chlamydia

Question 19

In order for PID to present, the infection must spread up the genital tract. What is the farthest end stage presentation?

Answer 19

Pyrosalpinx and a Tubo-Ovarian ABSCESS

Question 20

What is Fitz-Hugh-Curtis Syndrome?

Answer 20

Complication of PID

=> peritoneal inflammation

Question 21

What is a possible infant complication if the mother has PID?

Answer 21

Neonatal Conjunctivitis/blindness

Question 22

What 2/3 drugs can be given for the OUTPATIENT PID case?

Answer 22

Ceftriaxone + Doxycycline +/- Metronidazole

Question 23

What is the outpatient drug combo to treat PID?

Answer 23

Ceftriaxone + Doxycycline +/- Metronidazole

Question 24

For the INPATIENT treatment of PID, there are what 2 possible 2nd gen Cephalosporins?

Answer 24

Cefoxitin

Cefotetan

Question 25

INpatient treatment for PID combo?

Answer 25

(Cefoxitin OR Cefotetan) + Doxycycline

Question 26

If the patient is pregnant with PID, what is the drug combo?

Answer 26

Gentamycin + Clindamycin

Question 27

If the patient is pregnant with PID, what is drug treatment combo?

Answer 27

Gentamycin + Clindamycin

Question 28

MOA for Gentamycin?

Answer 28

(-) 30s protein synthesis

Question 29

What are the possible adverse effects of Gentamycin?

Answer 29

Nephrotoxic
Neurotoxic
Ototoxic