vitamins lecture 3 Flashcards

1
Q

what are the examples of Fat soluble vitamins?

A

A, D3, D2, E,K

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2
Q

what is an example of vitamin A?

A

retinol

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3
Q

where is the fat soluble vitamins absorbed in?

A

SI

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4
Q

what are FSV?

A

antioxidant

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5
Q

where do the FSV dissolve in?

A

lipids

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6
Q

where do the FSV circulates in?

A

lymph

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7
Q

where do the excessive FSV accumulate in?

A

liver and adipose

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8
Q

what is an active form of vitamin A?

A

retinal and retinoic acid

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9
Q

where are the vitamin A stored in?

A

liver

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10
Q

what are the functions of vitamin A?

A

synthesis of RNA
embryonic development
reproduction

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11
Q

what are the two types of vitamin A?

A

retinoids
carotenoids

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12
Q

what are the e.g. in retinoids?

A

retinol
retinal
retinoic acid

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13
Q

what are the e.g. in carotenoids?

A

provitamins A
nonprovitamins A

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14
Q

what are retinol?

A

they are preformed vitamin A that can be synthesised from retinal.

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15
Q

what can retinal be converted to?

A

retinoic acid

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16
Q

what is the regulation of vitamin A?

A

chylomicrons- lymph- thoracic duct-blood(muscles, adipose, eyes), then the unused vitamin A will go to the liver.

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17
Q

what are the sources of vitamin A:

A

lutein
lycopene
beta carotene

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18
Q

if you intake appropriate amount of lutein what does it result to?

A

decreased growth of breast tumours
decreases muscle degeneration

19
Q

what food are examples of lutein?

A

dark, green leafy vegetables.

20
Q

if you intake appropriate amount of lycopene which does it result to?

A

decreases risk of prostate cancer

21
Q

what are the examples of lycopene?

A

tomatoes, grapefruit and apricots

22
Q

what are the examples of beta carotene?

A

carrots and sweet potatoes

23
Q

what disorders does deficiency in vitamin A cause?

A

night blindness/ nyctalopia

increased risk of infections

xerophthalmia

hyperkeratosis.

24
Q

what does what is night blindness caused by?

A

deficiency in retinal

25
what are the two examples of toxicity in vitamin A?
carotenoid toxicity retinoic acid/isotretinoin
26
what are the negative effects of carotenoid toxicity?
blurred vision liver abnormalities reduce strength in the bones birth defects risk of lung cancer hypercarotemia
27
what are the negative effects of retinoic acid/ isotretinoin toxicity?
reduced size of sebaceous glands - decreases oil production improves ance
28
what is an example of vitamin D?
cholecalciferol
29
what is the deficiency caused by Vitamin D?
rickets
30
what are the functions of vitamin D?
exposed to sunlight vitamin D synthesised to the skin regulates the absorption of Ca2+ during bone formation. enhances the immune system improves muscle strength
31
what hormone is vitamin D activated by?
parathyroid hormone
32
what is an example of vitamin E?
Tocopherol
33
what deficiency is caused by deficiency of vitamin E?
hemolysis and anaemia oxidative degradation of polyunsaturated membrane phospholipids.
34
what is the function of vitamin E?
synthesised by plants most found in fatty tissues antioxidant properties provide integrity to the membrane
35
what does antioxidant property in vitamin E do?
reduces division of oxygen reagents and free radicals protects polyunsaturated fatty acids in membrane phospholipids from oxidative damage
36
what is an example of vitamin K ?
menaquinone
37
what are the types of vitamin K?
K1 K2
38
what are vitamin K1 synthesised by?
plants
39
what are vitamin K2 synthesised by?
gram positive bacteria in ileum and jejunum
40
what is vitamin K2 needed for?
synthesis of zymogens for blood clotting.
41
what are the functions of vitamin K?
normal blood clotting provides bone structure cell signalling lipid metabolism
42
what do vitamin K do ?
carboxylates and activates clotting factors
43
what are vitamin K essential for?
post translation modifications
44
what are the deficiency caused by vitamin K ?
clotting disorders decreased bone mineral density menorrhagia