vitamins 4 Flashcards
why is calcium important?
- important for blood clotting
- nerve function
- helps with contraction of the heart muscles
- bone developmental
what happens during oestoclast activity?
low ca+
release ca+
what happens during oesoblast activity?
high ca+
stores ca+
if they are very high amount of calcium in the body what can it lead to?
cardiac arrest
if they are very low amount of calcium in the body what can it lead to?
respiratory arrest
what is the name given to the multinucleated cells that are involved in calcium homeostasis?
oestoclasts
which hormone is secreted by the thyroid gland to regulate calcium homeostasis?
calcitonin
how do bisphosphates help to treat osteoporosis?
antiresorptive therapy
what are the oestoblasts embedded as?
oestocytes
what are the oestoblasts made up of?
collagen fibers
where is the Ca+ stored?
in the bone matrix
what is the low Ca+ secreted by?
parathyroid gland
what does cAMP signalling and calcium sensing receptor stimulate?
oestoclast activity- low Ca+ in the bones
what does PTH promote?
oestoclasts activity
loss of Ca+ in the kidney
formation of steroid hormone calcitriol
what is calcitriol?
steroid hormone- vit D in kidney
what does cacitrol promote?
oestoclast activity
uptake of Ca+ from the gut
decrease Ca+ in the kidney
what is calcitonin?
peptide hormone
what does calcitonin secrete?
high Ca+ in the thyroid gland
what does calcitonin inhibit?
Ca+ reabsorption in kidney
oestoclasts
what is osteoporosis?
faster loss of bones