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XY1110 > TCA cycle > Flashcards

TCA cycle Flashcards

1
Q

what is the main goal of TCA cycle?

A

to produce NADH and FADH2

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2
Q

what is the rate limiting enzyme of TCA cycle?

A

isocitrate dehydrogenase

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3
Q

what are the steps of the TCA cycle?

A
  1. acetyl - CoA
  2. citrate
  3. isocitrate
  4. alpha ketoglutarate
  5. succinyl- CoA
  6. succinate
  7. fumarate
  8. malate
  9. oxaloactetate
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4
Q

what will activate the TCA cycle?

A

ADP

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5
Q

what will inhibit the TCA cycle?

A

ATP
NADH
FADH2

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6
Q

what does succinate dehydrogenase produce?

A

FADH2

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7
Q

what does Alpha - ketoglutarate dehydrogenase and isocitrate dehydrogenase and malate dehydrogenase produce?

A

NADH

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8
Q

what is involved in acetyl- coA to citrate?

A

citrate synthase

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9
Q

what is involved in citrate to isocitrate?

A

aconitase

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10
Q

what is involved in isocitrate to alpha- ketoglutarate?

A

isocitrate dehydrogenase

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11
Q

what is involved in alpha- ketoglutarate to succinyl- CoA?

A

alpha- ketoglutarate dehydrogenase

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12
Q

what is involved in succinyl- CoA to succinate?

A

succinate thiokinase

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13
Q

what is involved in succinate to fumarate?

A

succinate dehydrogenase

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14
Q

what is involved in fumarate to malate?

A

fumarase hydrodase

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15
Q

what is involved in malate to oxaloacetate?

A

malate dehydrogenase

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16
Q

How does thermogenin, a protein expressed in brown adipose cells, generate heat?

A

uncouples electron transport

17
Q

Which enzyme in the TCA cycle is inhibited by the toxin fluroacetate?

A

aconitas

18
Q

During the first stage of acetyl CoA synthesis by the pyruvate dehydrogenase complex; what is removed from pyruvate?

A

carbon dioxide

19
Q

In reactive oxygen scavenging; which reactive centre does peroxidase catalase use to convert two hydrogen peroxide ions to water and oxygen?

A

iron hem group

20
Q

Which complex in the electron transport chain is inhibited by cyanide and carbon monoxide?

A

comple IV

21
Q

For each molecule of glucose that enters glycolysis, how many times can the TCA cycle proceed?

A

2

XY1110 (30 decks)

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