Glucogenogeneis Flashcards
what is gluconeogenesis?
it is a process where glucose is formed from non-carbohydrates components such as glycerol, lactate and amino acids.
when does glucogneogenesis occurs?
during fasting- when the body needs to make glucose but does not have glucose
what is the key part of this process?
glucose 6 phosphate
what is the rating limiting step for glucogenogenesis?
fructose 1,6 bisphosphate.
what is fructose 1,6 bisphosphate activated by?
citrate
what is fructose 1,6 bisphosphate inhibited by?
AMP, fructose 1,6 bisphosphate
what does glucagon inhibit?
glycolysis
what does glucagon promote?
glucogenogenesis
if you have insulin what do you don’t have?
glucagon
if you do not have insulin what do you have?
glucagon
what are the steps of this process?
glucose
glucose 6 phosphate
fructose 6 phosphate
fructose 1,6 bisphosphate
phosphpend pyruvate
oxaloacetate
pyruvate.
what enzyme is involved in phosphoend pyruvate to oxaloactetate?
phosphoend pyruvate carboxylkinase- requires GTP.
what enzyme is involved in oxaloacetate to pyruvate?
pyruvate carboxyl
what is pyruvate carboxyl activated by?
Acetyl - CoA
In gluconeogenesis, which phospho-nucleotide inhibits the activity of pyruvate carboxylase and phosphoenolpyruvate carboxykinase?
ADP
