Glycogenolysis Flashcards
what is glycogenolysis?
it is the break down of glycogen into glucose 1 phosphate and glucose.
how many ATP is produced from the glycogen?
3
what is glycogenolysis generated by?
anaerobically
in the muscle what is glycogen used as?
rapid source of energy storage
in the liver what is glycogen used as?
it is used to maintain blood glucose levels especially during fasting or between meals.
what does glycogenolysis begin with?
glycogen phosphorylase- enzyme
what does glycogen phosphorylase target?
free end of glycogen by targeting the alpha 1-4 glycosidic bond.
when the glycogen phosphorylase targets the 1-4 alpha glycosidic bonds what does it produce?
glucose 1 phosphate
what are the steps involved in glycogenolysis?
- glycogen phosphorylase
- oligo alpha 1-4 to alpha 1-4 glucantransferase
- amyloid alpha 1,6 glucosidase- debranching
- phosphoglucomutase
- phosphatase.
what does glucosidase hydrolyses?
alpha 1-6 bond
what does phosphorylation activate?
glycogen phosphorylase
what does phosphorylation inhibit?
glycogen synthase
where in the body is glycogen mainly utilised?
liver and skeletal muscles
what is the regulation of glycogen in the liver?
- glucose 1 phosphate
- glucose 6 phosphate
- glucose
what is the regulation of glycogen in the skeleton muscles?
- glucose 1 phosphate
- glucose 6 phosphate
- glycolysis
