Virusriket Flashcards

1
Q

Olika virusindelningar? (5)

A

RNA/DNA, små/stora, typ av sjukdom, spridning, realisation

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2
Q

Hur ser ett virus ut? (5)

A

RNA/DNA, nucleo-kapsid, tegument, lipid-kappsel, kappsel-proteiner

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3
Q

Kapsidstrukturer? (2)

A

Icosahedral (VP1-3), helikal (alla har kapsel)

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4
Q

Beskriv översiktligt virus replikatinoscykel? (6)

A

Inbindning, penetration, avklädning, syntesfas, sammanfogningsfas, frigörelsefas

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5
Q

Tropism? (3)

A

Värd, organ, cell tropism

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6
Q

Hur sker inbindningen?

A

VAP på kapsel/kapsid binder till receptor på målcell (prot/kolhydrat)

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7
Q

Hur sker penetration?

A

Nakna virus: endocytos. Höljevirus: membranfusion, endocytos, syncytier.

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8
Q

Hur sker avklädning?

A

Receptorbindning/pH/proteaser => sönderfall av kapsid. RNA => cytoplasman. DNA => proteaser.

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9
Q

Hur sker syntesfasen? (6)

A

DS DNA, SS DNA, +RNA, -RNA, DS RNA, retro. Proteinsyntesen sker som vanligt fast med virus RNA.

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10
Q

Hur sker sammanfogningsfasen?

A

När virusprot finns i tillräcklig konc sätts de ihop. DNA virus sätts ihop i cellkärnan. Höljet fås vid avknoppning.

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11
Q

Hur sker frigörelsefasen?

A

Lysering, exocytos, avknoppning.

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12
Q

Hur sprider sig virus till andra celler?

A

Infekterar en cell som åker iväg till annat ställe i kroppen. tex lunga, blod, hud.

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13
Q

Olika mutationshastigheter i olika virus?

A

RNA > DNA, viruspolymeras > värdpolymeras

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14
Q

Olika typer av mutationer? (3)

A

Addition, deletion, punktmutation

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15
Q

Effekt av mutationer på protein? (4)

A

Tyst, utbyte, nonsense, frame-shift

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16
Q

Vad händer om två virus infekterar samma cell? (2)

A

Reassortment, Recombination