viruses Flashcards

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1
Q

what is a virus?

A

an infectious agent

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2
Q

what are the living features of a virus?

A

can mutate and reproduce rapidly (only in a living host cell)

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3
Q

what are the non-living features of a virus?

A

no cytoplasm or cellular organelles

does not carry out metabolism– replicates using host cell’s metabolic machinery

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4
Q

viruses don’t grow and divide, instead ________

A

new viral components are synthesized and assembled within the infected host cell

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5
Q

genome

A

the virus’s genetic material

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6
Q

the genome can be ________ or _______, but never both

A

single stranded / double stranded

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7
Q

the genome codes for the ___________

A

synthesis of viral components and viral enzymes for replication

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8
Q

capsid

A

protein shell surrounding the genome

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9
Q

what is the function of the capsid?

A

protect and introduce the genome into host cells

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10
Q

what is a virus that is just a genome surrounded by a capsid called?

A

nucelocaspid or naked virus

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11
Q

___________ project out from the capsid and binds the virus to a susceptible host

A

attachment proteins

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12
Q

envelope

A

surrounding a polyhedral or helical nucleocaspid

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13
Q

where does the envelope come from?

A

the host cell’s nuclear membrane, vacuolar membrane, or outer cytoplasmic membrane

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14
Q

the envelope is usually of host cell origin, but the virus incorporates _________, which appear as ________ spikes

A

proteins of its own / gycoprotein

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15
Q

what is the function of the glycoprotein spikes?

A

attaching the virus to receptors on susceptible host cells

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16
Q

how does a virus cause disease?

A

uses another living host organism to reproduce

  • there are so many viruses in the cell that it bursts and the viruses are free to move on to other cells in the host
  • process repeats
17
Q

what are virus vaccines made of?

A

inactivated or attenuated viruses

18
Q

inactivated virus

A

does not replicate in a host cell

19
Q

attenuated viruses

A

genetically altered; cannot cause disease

20
Q

why are viral infections difficult to cure?

A

once inside the host, most substances that destroy the virus are also harmful to the host organism

21
Q

what were the first viral vaccinations for?

A

measles, mumps, rubella

22
Q

what are current viral vaccinations?

A

hepatitis A and B, chickenpox, smallpox, rabies

23
Q

antiviral drugs

A

interfere with the synthesis of viral nucleic acid or with the formation of viral caspids during replication

24
Q

antibiotics

A

no use for fighting viruses

25
Q

why are antibiotics not used in curing viral infections?

A

they attack the metabolism of a bacterial cell

-viruses do not have metabolism

26
Q

2 ways the body fights viruses

A

white blood cells

interferon

27
Q

white blood cells

A

engulf viruses in the blood and “digest” them

28
Q

interferon

A

a protein produced by cells when exposed to a virus

  • binds the cell membranes of neighbouring cells
  • interferes with the ability of a virus to enter the cell
29
Q

public health strategy

A

a coordinated effort to track, research, and reduce the incidence of specific health problems in a population

30
Q

vaccination

A

the process of giving a vaccine by mouth or injection to provide active immunity against a disease

31
Q

what are infectious diseased caused by?

A

pathogens (viruses, bacteria, fungi) entering the body

32
Q

what organ is the first line of defense that stops pathogens?

A

skin

33
Q

what does the immune system do to fight off pathogens?

A

send a flow of white blood cells (phagocytes) and dissolved substances to the site of the infection, causing inflammation

34
Q

what does bone marrow produce to help fight off pathogens?

A

white blood cells and disease-fighting molecules

35
Q

antigen

A

any material that the body considers foreign and triggers phagocytes

36
Q

antibodies

A

specialized proteins found in phagocytes