Viruses Flashcards

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1
Q

Do viruses share characteristics with cells?

A

No

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2
Q

What is the virion and what does it contain?

A

Infectious viral particle
Nucleic acid surrounded by protein coat
Capsid

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3
Q

What is the protein coat for?

A

A protection and transmisttion

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4
Q

What is nucleic acid?

A

DNA or RNA never both

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5
Q

What is the capsule made of?

A

Capsomere submits
One or several types of proteins

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6
Q

What does the envelope contain?

A

Lipids
Proteins
Carbohydrates

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7
Q

What is the envelope?

A

A lipis bilayer that surrounds the viral capsid

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8
Q

Are all viruses enveloped?

A

No

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9
Q

How are viral genomes classified?

A

Nucleic type
Strategy for replication
Morphology

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10
Q

Can viral gemones be RNA or DNA?

A

Both

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11
Q

Do Viral genomes have to be singles stranded or double stranded?

A

Both

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12
Q

What are the different types of viruses?

A

HIV
Hepatitis B
Ebola virus
Advenovirus
Influenza
Bacteriophage

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13
Q

What is the basis of host range?

A

The ability to hind to the host cell

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14
Q

What is the attachment called whith the interaction between ligands on the virus surface and the receptors on the cell surface?

A

Lock and key

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15
Q

What is the lytic viral infection cycle?

A

Attachment
penetartion
Uncoating
Replication
Assembly
Viron release

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16
Q

What is it meant by attachment in the lytic viral infection cycle?

A

Proteins on the capsid or envelope interact specifically with receptors on the host cell surface

17
Q

What is it meant by penetration in the lytic viral infection cycle?

A

Attachment induces conformational changes in the virus resulting in fusion of membranes
Some viruses can also enter ny endocytosis

18
Q

What is it meant by uncoating in the lytic viral infection cycle?

A

Viral capsid is removed and degraded by viral or host enzymes
Viral DNA is released

19
Q

What is it meant by replication in the lytic viral infection cycle?

A

Transcription and translation of the viral genome is initiated
New viral genomes and viral proteins are made

20
Q

What is it meant by assembly in the lytic viral infection cycle?

A

Viral proteins are packaged with the newly synthesised ciral genome into virons ready to be released from the host cell

21
Q

What is it meant by viron release in the lytic viral infection cycle?

A

LYSIS or BUDDING
Lysis results in death of the cell and the viruses are cytolytic
Budding results in the acquisition of a viral envelope, do not kill the cell and are known as cytopathic

22
Q

What are the differences between lytic and lysogenic cycles of bacteriophage?

A

Lysic results in lysis of the host cell and lysogenic do not lyse

In lytic the viral DNA is not intergrated into the host genome whereas in lysogenic the viral DNA is integrated into the host genome and the prophage stage is when viral genome is part of the host genome

Lytic, the viral DNA replication is seperate from host DNA replication and in lysogenic the viral DNA is replicated along with normal host DNA replication

Lytic progeny virus is released during lysis or budding and in lysogenic the progeny virus is not released until switched back to lytic cycle

Example of lysic is influenza that effects the lungs
Example of lysogenic is herpes virus that can be undetected for a long period of time