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PH151 > Virus > Flashcards

Virus Flashcards

1
Q

Non living obligate intracellular parasites

A

Virus

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2
Q

Consist of a nucleic acid surrounded by a protein coat

A

Virus

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3
Q

May consist of a double stranded and single stranded DNA and RNA

A

Viral genomes

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4
Q

Protein shell enclosing the viral genome

A

Capsids

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5
Q

Protein subunit of capsid

A

Capsomeres

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6
Q

Surrounds the capsids

A

Viral envelopes

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7
Q

Studied tobacco mosaic disease

First scientist to voice the concept of a virus

A

Martinus Beijernick

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8
Q

Cristallized the infectious particle tobacco mosaic virus (TMV)

A

Wendell Stanley

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9
Q

Capsid + Nucleic Acid

A

Nucleocapsid

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10
Q

Nucleic Acid + Capsid + Envelope

A

Virion

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11
Q

Morphologic units on surface of icosahedralvirus particles

A

Capsomeres

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12
Q

Virus particle is composed of

A

Covering

Inner core

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13
Q

Covering is composed of

A

Capsid (protein)

Envelope (not found in all viruses)

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14
Q

Inner core is composed of

A 
Nucleic acid molecule (DNA or RNA)
Various protein (enzymes)
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15
Q

Virus size

A

18-300 nm diameter

180-400 nm length

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16
Q

Viral shapes

A

Icosahedral
Helical
Complex

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17
Q

Examples of icosahedral viruses

A

Herpes simplex virus
Poliovirus
Parvovirus

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18
Q

Example of helical viruses

A

Rabies virus

Tobacco mosaic virus

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19
Q

Example of complex viruses

A

Smallpox virus
T4 bacteriophage
Influenza virus

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20
Q

Viral structure

A

Naked virus

Enveloped virus

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21
Q

Either DNA or RNA
Linear or circular
Single or double stranded
Segmented or non segmented

A

Nucleic Acid

22
Q

Protection against inactivation by nucleases

Aids in attachment to host, virus replication, structural symmetry, and determination of antigenic property

23
Q

Found in envelopes

Derived from host cell

24
Q

Present as glycoproteins in envelope
Virus-coded
Also function as antigens

A

Carbohydrates

25
Q

Example of a cell culture

A

HeLa cell line

26
Q

Detection of virus infected cells

A

Cytopathic effect
Hemagglutination test
Plaques

27
Q

A single virus in the initial suspension

28
Q

Viral concentration is expressed in terms of

A

Plaque-forming units (PFU)

29
Q

Viral identification

A

Western blotting

Polymerase chain reaction

30
Q

Virus is detected and identified by its reaction with antibodies

A

Western Blotting

31
Q

Used to rapidly amplify a specific target gene segment in a DNA
Performed in vitro

A

Polymerase chain reaction (PCR)

32
Q

Basis of viral classification

A 
Genome
Structure
Route of transmission
Immunologic properties
Pathology/symptomatology
33
Q

Examples of route of transmission

A

Enteric
Respiratory
Zoonotic
Sexually-transmitted

34
Q

Viral Replication

A

Obligate intracellular parasites

- only replicates within host cell

35
Q

Viral replication process

A 
Attachment
Penetration
Biosynthesis
Maturation
Release
36
Q

Viruses that infect bacteria

A

Bacteriohages

37
Q

Types of bacteriophages

A

Lytic or virulent

Temperate or lysogenic

38
Q

Released by cell lysis

A

Lytic or virulent

39
Q

No lysis occurs but lytic cycle may be spontaneously expressed

A

Temperate or lysogenic

40
Q

Examples of viral diseases in humans

A 
Flu (by Influenza)
Dengue
Viral meningitis
Hepatitis (A, B, and C)
Polio virus
Poliomyelitis
Small pox
Measles
Mumps
German measles
Chickenpox
Shingles
Herpex simplex virus
Human papilloma virus
Human immunodeficiency virus
Ebola
41
Q

Mosquito causing dengue

A

Aedes aegypti

42
Q

Caused by a variety of virus

A

Viral meningitis

43
Q

Viral infection in the liver

A

Hepatitis (A, B, and C)

44
Q

Infects spinal cord and nervous system
Contagious
Results to inability to move or paralysis

A

Polio Virus

45
Q

Poliovirus spread mainly through the

A

Fecal-oral route

46
Q

Measle causing virus

A

Rubeola virus

47
Q

German measles causing virus

A

Rubella virus

48
Q

Kills cells causing them to rupture
Damages almost every organ
Wrecks immune system

49
Q

Rabies causing virus

A

Rhabdovirus

50
Q

Consist of a single piece of nucleic acid (RNA) without protective coat
Infect plants

51
Q

Contain only protein
No nucleic acid
Smallest infectious agent

52
Q

Example of prion diseases

A

Mad cow disease

Creutzfeld Jacob Disease

PH151 (15 decks)

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