Viral Infections Flashcards

1
Q

What is the viral structure of the herpes virus? (2)

A
  • Enveloped

- dsDNA

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2
Q

Name the 3 Alpha-Herpes viruses

A
  • HSV1
  • HSV2
  • VZV
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3
Q

Name the 4 Beta-Herpes viruses

A
  • CMV
  • HHV6
  • HHV7
  • Simian herpes 8
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4
Q

Name the 2 Gamma-Herpes viruses

A
  • EBV

- HHV8

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5
Q

How does HSV1 work?

What can reactivate this virus?

A
  • Infects epithelial cells
  • HSV1 sheds lipid coat and the DNA migrates down the nerve axon
  • Triggers such as trauma reactivate the virus
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6
Q

What are the causative viruses of primary herpetic gingivostomatitis?

A

HSV1 & HSV2

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7
Q

Clinical features of primary herpetic gingivostomatitis?

Dental (3)
General (3)

A
  • Blood crusted lips
  • Widespread oral painful ulcers
  • Swollen gingiva
  • Fever
  • Headache
  • Cervical lymphadenopathy
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8
Q

Treatment of primary herpetic gingivostomatitis? (4)

A
  • Reassurance
  • Limit lip/mouth contact
  • Chlorhexidine mouthwash
  • Acyclovir
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9
Q

Herpes Labialis;

Clinical features
Triggers (5)
Treatment (3)

A
  • Burning and tingling followed by erosion of vesicles around mouth
  • Sunlight, Trauma, Stress, Fever, Menstruation
  • Education, Acyclovir, Suncream
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10
Q

What are the sidemen HSV clinical presentations? (3)

A
  • Eczema herpeticum
  • Erythema multiforme
  • Herpetic whitlow
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11
Q

Chickenpox;

Causative virus?
Prevalence?
Transmission?
Incubation period?

A
  • VZV
  • 90% of adults have antibodies to the virus
  • Direct contact or droplet
  • 14 days
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12
Q

What is shingles?

Where does the virus stay dormant?

A
  • Reactivation of VZV after being latent

- In the dorsal root ganglia

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13
Q

What may be prescribed to treat shingles?

Why is it important to prescribe ASAP?

A
  • Acyclovir (800mg five times a day for 7-10 days)

- Reduce likelihood of post-herpetic neuralgia

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14
Q

What is Ramsay Hunt syndrome caused by?

A

VZV affecting a facial motor nerve

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15
Q

What are the clinical presentations of Ramsay Hunt syndrome? (3)

A
  • Ipsilateral LMN facial palsy
  • Rash in the external ear
  • Loss of taste sensation of anterior 2/3 of tongue
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16
Q

What does HSV1 stand for?

A

Herpes Simplex Virus 1

17
Q

What does VZV stand for?

A

Varicella Zoster Virus

18
Q

What does EBV stand for?

A

Epstein-Barr Virus

19
Q

Infectious Mononucleosis;

  • Causative virus?
  • Transmission?
  • Prevalent group?
A
  • EBV
  • Transmitted by salivary droplets
  • Teenager and early adolescence
20
Q

How does EBV cause Infectious Mononucleosis?

A
  • EBV infect B-lymphocytes
  • T-lymphocytes react to the infected B-cells and become atypical lymphocytes
  • Lymphoid proliferation in the blood, lymph nodes and spleen
21
Q

What is the clinical presentation of Infectious Mononucleosis? (6)

A
  • Lymph node enlargement
  • Fever
  • Pharyngeal inflammation
  • Petechiae in palate
  • Oral ulceration
  • Gingival bleeding
22
Q

What is Burkitt’s lymphoma and what virus is it caused by?

A
  • Aggressive swelling of jaw

- EBV

23
Q

Oral Hairy Leukoplakia;

  • Causative Virus?
  • Prevalence?
  • Site?
A
  • EBV
  • HIV and Immuno compromised patients
  • Lateral border of tongue
24
Q

What is the clinical presentation of Oral Hairy Leukoplakia?

A

Well demarcated corrugated white lesion, flat or plaque-like or papillary-villous

25
Q

What virus causes mumps?

A

Paramyxoviridae

26
Q

What are the potential complications that could arise from Mumps? (3)

A
  • Meningitis
  • Encephalitis (inflammation of brain)
  • Transient deafness
27
Q

What is the the structure of the Papillomavirus?

A
  • Non enveloped

- dsDNA virus