Gastroenterology: Lower GIT diseases Flashcards
What does the Lower GIT anatomically consist of? (4)
- Small intestine
- Large intestine
- Rectum
- Anus
What are the 3 components of the small intestine?
- Duodenum
- Jejunum
- Ileum
What are the 4 components of the large intestine?
- Colon
- Ascending segment
- Transverse segment
- Descending segment
What are the two main functions of the small intestine?
- Digestion
- Absorption
Where in the small intestine are the following substances absorbed?
- Iron + folate
- Gastric intrinsic factor + Vitamin B12
- Bile salts , fats and fat soluble vitamins
- Other substances
- Duodenum
- Terminal Ileum
- Terminal Ileum
- Jejunum
Name two common small intestine diseases
- Coeliac disease
- Crohn’s disease
What is steatorrhoea?
The presence of excess fat in faeces (fatty stools)
What is coeliac disease
A disease in which the small intestine is hypersensitive to gluten, leading to difficulty in digesting food.
A toxic reaction to the α-gliadin component of gluten is a characteristic of which disease?
Coeliac disease
At what age can coeliac disease present itself?
Any age
Coeliac disease can cause villous atrophy (malabsorption), what are the consequences of this? (3)
- Growth retardation (child)
- Vitamin deficiencies
- Mineral deficiencies
What are some clinical manifestations of malabsorption?
3 Dental
3 General
- Glossitis
- Burning mouth
- Angular chelitis
- Tiredness
- Malaise
- Easy bruising
When investigating Coeliac disease what will these tests determine;
- Full blood count?
- Haematinics (nutrients) screen?
- Stool examination?
- Serology? (what antibodies are present)
- Endoscopy?
- Anaemia
- Vitamin B12, Folate, Iron deficiency
- Excess fat
- Antigliadin and antiendomysial antibodies
- Villous atrophy
What is the dental relevance of coeliac disease? (3)
- Dental enamel defects
- Glossitis
- Angular cheilitis
How would you manage coeliac disease?
Gluten free diet for life
ONLY treatment
What are the two main functions of the large intestine?
- Recovery of water and electrolytes
- Formation, storage and expulsion of faeces