viral Causes of Oral Ulcerations

Question 1

how many types of herpes simplex virus is there

Answer 1

2
type 1
type 2

Question 2

when is type 1 commonly acquire

Answer 2

childhood

Question 3

what type of HSV is the cause of oral lesions

Answer 3

type 1

Question 4

what is a common way of infection with HSV

Answer 4

through saliva contact

saliva acts as resevoir

Question 5

what si a common manifestation of HSV1

Answer 5

primary gingivostomatitis

Question 6

what does primary gingivostomatitis infect

Answer 6

disease of pre school children

Question 7

what does primary gingivostomatitis present like

Answer 7

skin around mouth = vesicles 1-2mm
pustules
ulcers
scabs

Question 8

what are th systemic upsets of primary gingivostomatitis

Answer 8

fever
local lymphadenopathy (enlarged lymph nodes)
dehydration and malnourishment due to reluctance to eat/drink

Question 9

what si the recovery period of primary gingivostomatitis

Answer 9

up to 3 weeks
may spread beyond mouth
acyclovir treatment - shorten course but not rid of immediately

Question 10

what is latency

Answer 10

after primary infection
inactive virus in CNS trigem nerve
can reinfect mucosal surfaces if reactivated

Question 11

what causes a cold sore

Answer 11

reactivation from nerves causes active infection

from various stimuli

Question 12

how are cld sores treatment

Answer 12

acyclovir therapy or suppression

Question 13

are all activations symptomatic

Answer 13

no

Question 14

does aciclovir have latency

Answer 14

no

Question 15

how does natural history of cold sores affect frequency

Answer 15

decreasing

Question 16

oral herpetic lesions usually caused by

Answer 16

HSV1

Question 17

what is herpetic whitlow

Answer 17

occupational hazard
use of gloves prevent
infection at nail folds of fingers/thumb

Question 18

what is one of the most severe manifestations of HSV

Answer 18

herpes simplex encephalitis (brain tissue inflam/infection)

fatal

Question 19

what is herpangina

Answer 19

at back of mouth

vesicles/ulcers on soft palate

Question 20

wha causes herpangina

Answer 20

enteroviruses

- coxsackie not HSV

Question 21

who does herpangina affect most

Answer 21

pre school children

Question 22

how is herpangina diagnosed

Answer 22

clinically or by PCR test swab in viral medium

Question 23

what causes hand, foot and mouth disease

Answer 23

enteroviruses - coxsackie

family outbreaks

Question 24

what are aphthous ulcers

Answer 24

non viral
self limit
recurring painful ulcers

Question 25

what ar the aphthous ulcers appearance

Answer 25

round or ovoid and have inflam halos

Question 26

where and when do aphthous ulcers occur

Answer 26

confined to mouth
absence of systemic disease
in childhood
each user lasts 3 weeks

Question 27

what are the types of recurrent ulcers assc with systemic disease non viral

Answer 27

behcets disease
gluten sensitive enteropathy or inflame bowel disease 
reiters disease
drug reactions
skin diseases

Question 28

what is behcets disease

Answer 28

recurrent oral ulcers
genital ulcers
uveitis (eye inflam iris)
inv GI, CV

Question 29

what are some skin diseases of ruccurent ulcers assc with systemic disease

Answer 29

lichen planus
pemphigus
pemphigoid

Question 30

how does primary syphilus present

Answer 30

chancre

• painless indurated - hard to touch
• commonly genitals but oral lesions also
• lead to secondary or tertiary