viral Causes of Oral Ulcerations Flashcards
how many types of herpes simplex virus is there
2
type 1
type 2
when is type 1 commonly acquire
childhood
what type of HSV is the cause of oral lesions
type 1
what is a common way of infection with HSV
through saliva contact
saliva acts as resevoir
what si a common manifestation of HSV1
primary gingivostomatitis
what does primary gingivostomatitis infect
disease of pre school children
what does primary gingivostomatitis present like
skin around mouth = vesicles 1-2mm
pustules
ulcers
scabs
what are th systemic upsets of primary gingivostomatitis
fever
local lymphadenopathy (enlarged lymph nodes)
dehydration and malnourishment due to reluctance to eat/drink
what si the recovery period of primary gingivostomatitis
up to 3 weeks
may spread beyond mouth
acyclovir treatment - shorten course but not rid of immediately
what is latency
after primary infection
inactive virus in CNS trigem nerve
can reinfect mucosal surfaces if reactivated
what causes a cold sore
reactivation from nerves causes active infection
from various stimuli
how are cld sores treatment
acyclovir therapy or suppression
are all activations symptomatic
no
does aciclovir have latency
no
how does natural history of cold sores affect frequency
decreasing
oral herpetic lesions usually caused by
HSV1
what is herpetic whitlow
occupational hazard
use of gloves prevent
infection at nail folds of fingers/thumb
what is one of the most severe manifestations of HSV
herpes simplex encephalitis (brain tissue inflam/infection)
fatal
what is herpangina
at back of mouth
vesicles/ulcers on soft palate
wha causes herpangina
enteroviruses
- coxsackie not HSV
who does herpangina affect most
pre school children
how is herpangina diagnosed
clinically or by PCR test swab in viral medium
what causes hand, foot and mouth disease
enteroviruses - coxsackie
family outbreaks
what are aphthous ulcers
non viral
self limit
recurring painful ulcers
what ar the aphthous ulcers appearance
round or ovoid and have inflam halos
where and when do aphthous ulcers occur
confined to mouth
absence of systemic disease
in childhood
each user lasts 3 weeks
what are the types of recurrent ulcers assc with systemic disease non viral
behcets disease gluten sensitive enteropathy or inflame bowel disease reiters disease drug reactions skin diseases
what is behcets disease
recurrent oral ulcers
genital ulcers
uveitis (eye inflam iris)
inv GI, CV
what are some skin diseases of ruccurent ulcers assc with systemic disease
lichen planus
pemphigus
pemphigoid
how does primary syphilus present
chancre
- painless indurated - hard to touch
- commonly genitals but oral lesions also
- lead to secondary or tertiary
