M28 Protozoa Flashcards
what is a a protozoa
single celled eukaryote
lack cell wall
free living anaerobes
some paratsitc
what ar some characteristics of protozoa
have nuc env diff compartments has histone proteins has cytoskel may/not have mito
what are the major protozoan disease of man
leishmaniasis 150 million
malaria - 3.3 bill
toxoplasma - 2 bill
(oral protozoa 4-52%)
what are the protozoa of the oral cavity
trichomonas tenax
trichommonas vaginalis
entamoeba gingivalis
what is trichomoniaisi
T vaginalis STD
infertile
pelvic inflam
cervical neoplasia
why else can T tenax and T vaginalis cause
broncho pulmonary infection
assc lung disease
how is trichomoniasis treated
metronidazole
what is trichomonad tenax
saprophyte
lactoferrin
assc with poor oral hygiene
21% perio disease
when is entamoeba seen
amoebic dysentry
amoebic liver abscess
other harmless sp
what is entamoeba gingivalis
ingest microbes
cause perio disease
pulmonary abscess
carriage often
what are two types of gastro intestinal diseases
entameobosis
cryptosporodiosos
what is entameobosis nd how treat
infect - cysts shed = amoebic dysentry or colitis
treat = metronidazole and chloroquinone
what is cryptosporidiosos
poor hygiene
rehydration
cramps
diarrhoea
how bad is the effect of malaria on pop
3.3 bill at risk
how’s malaria transmitted
by mosquito
ANOPHELES MOSQUITO
what protozoa causes malaria
plasmodium falciparum (most dangerous) plasmodium vivax/ovale/malariae
where are mosquitos found
stagnant water in hot countries
what is the infecttous vector for malaria
female as male doesn’t fee don blood
bite between sunset and rise
what is the lifecycle of mosquito
infects - release sporozoites which travel to liver and divide
merozoites released and infect erythrocytes
remodelly RBC = exp surface P’s, prod knobs and mauer clefts
when do RBC rupture
48hrs = 16-32 merozites released
derdtaion decrease oxygen carriage
what are the symptoms of malria
flu high fever successive waves delirium seizures death
what are some common drugs to prevent malaria
chloroquine
mefloquine
deoxycline
how is malaria treated
prompt
quinine
chloroquine
combination therapy so no resist
what is toxoplasma
obligate intracellular parasite
life cycle involving rents
what is toxoplasmosis
asymptomatic
treat wit sulphadiazine
assc with risk taking activates
