M28 Protozoa Flashcards

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1
Q

what is a a protozoa

A

single celled eukaryote
lack cell wall
free living anaerobes
some paratsitc

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2
Q

what ar some characteristics of protozoa

A
have nuc env 
diff compartments
has histone proteins 
has cytoskel
may/not have mito
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3
Q

what are the major protozoan disease of man

A

leishmaniasis 150 million
malaria - 3.3 bill
toxoplasma - 2 bill
(oral protozoa 4-52%)

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4
Q

what are the protozoa of the oral cavity

A

trichomonas tenax
trichommonas vaginalis
entamoeba gingivalis

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5
Q

what is trichomoniaisi

A

T vaginalis STD
infertile
pelvic inflam
cervical neoplasia

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6
Q

why else can T tenax and T vaginalis cause

A

broncho pulmonary infection

assc lung disease

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7
Q

how is trichomoniasis treated

A

metronidazole

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8
Q

what is trichomonad tenax

A

saprophyte
lactoferrin
assc with poor oral hygiene
21% perio disease

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9
Q

when is entamoeba seen

A

amoebic dysentry
amoebic liver abscess
other harmless sp

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10
Q

what is entamoeba gingivalis

A

ingest microbes
cause perio disease
pulmonary abscess
carriage often

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11
Q

what are two types of gastro intestinal diseases

A

entameobosis

cryptosporodiosos

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12
Q

what is entameobosis nd how treat

A

infect - cysts shed = amoebic dysentry or colitis

treat = metronidazole and chloroquinone

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13
Q

what is cryptosporidiosos

A

poor hygiene
rehydration
cramps
diarrhoea

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14
Q

how bad is the effect of malaria on pop

A

3.3 bill at risk

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15
Q

how’s malaria transmitted

A

by mosquito

ANOPHELES MOSQUITO

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16
Q

what protozoa causes malaria

A
plasmodium falciparum (most dangerous)
plasmodium vivax/ovale/malariae
17
Q

where are mosquitos found

A

stagnant water in hot countries

18
Q

what is the infecttous vector for malaria

A

female as male doesn’t fee don blood

bite between sunset and rise

19
Q

what is the lifecycle of mosquito

A

infects - release sporozoites which travel to liver and divide

merozoites released and infect erythrocytes

remodelly RBC = exp surface P’s, prod knobs and mauer clefts

20
Q

when do RBC rupture

A

48hrs = 16-32 merozites released

derdtaion decrease oxygen carriage

21
Q

what are the symptoms of malria

A
flu 
high fever
successive waves
delirium 
seizures 
death
22
Q

what are some common drugs to prevent malaria

A

chloroquine
mefloquine
deoxycline

23
Q

how is malaria treated

A

prompt
quinine
chloroquine
combination therapy so no resist

24
Q

what is toxoplasma

A

obligate intracellular parasite

life cycle involving rents

25
Q

what is toxoplasmosis

A

asymptomatic
treat wit sulphadiazine
assc with risk taking activates