Infectious Mononucleosis Flashcards
what is infectious mononucleosis aka
glandular fever
when does GF occur most
young adults
what is the basic presentation of GF
fever
enlarged lymph nodes
sore throat/pahryngitis/tonsilitis
malaise/lethargy
what are some other signs and symptoms of GF
jaundice/ hepatitis rash leucocytosis atypical lymphocytes splenomegaly palatal petechiae
what si the prognosis and complications of GF
protracted - self limit anaemia thrombocytopenia splenic rupture upper airway obstruction increased risk lymphoma
what virus causes GF
epstein barr virus
what is EBV
virus of herpes family - persistent infection of epi
what are the two phases of EBV infection
primary - early childhood rarely leads to GF
if occurs >10y.o.a = GF
what si the course of treatment for GF
bed rest
paracetamol
no sport
corticosteroids role in complicated cases
wat are the means of lab confirmation of GF
heterophiles Ab - paul bunnell test - monospot test epstein barr virus IgM blood count and film
what are some cases which can lead to similar illness to GF
cytomegalovirus toxoplasmosis primary HIV infection - few weeks after initial infection seroconversion illness