M1 Revision Flashcards
what re the man div of living orgs
plants
animals
micro orgs
what re the man div of micro orgs
algae
fungi
bateria
protozoa
what si size related
complexity
how quick grow and evolve
how far does a spore travel in comparison to the other viruses
further think cough
what are other process need to be aware of
cell cycle/ prolif
evolution (resistance)
evasion
colonisation
what are the basic features of prokaryotic cell
small and simple primitive intrcellular strutture circular chromosome peptidoglycan cell wall ribosome (70s)
what are th basic features of a eukaryotic cell
large and complex internal memo and mem bound organs linear chromo cell envelope or rigid cell wall ribo (80s)
what is the generalisation of eukaryotic structure
compartmentalised
what are some internal features of eukaryote
vacuoles chloroplast - in plant mito ribo golgi nucleolus ER plasma mem
what are some external features of eukaryotic cell
cell wall
capsule
cilia
flagella
why is prokaryotic cytoplasmic mem more imp
imp barrier of in and out
resp events = Photomotive force
what is important about cell wall
structural barrier
(adhesins, in/out)
chem reactions
(energy, transC, transL)
what do cell walls contain
peptidoglycan
what s peptidoglycan
sugar lattice
peptide bridges
what does ftsI encode
PBP3
penicillin binding protein
what is FtsI
transmembrane protein
what is transpeptidase
enzyme cross links peptide side chains in transpepetidation
what is the target of penicillin
FtsI
what is the cell wall like in gran -ve
thin cell wall located between inner and outer mem
what is cell wall like in gam +ve
thick multilayer cell wall and cytoplasmic mem
what are the cell wall basic features
rigid layer
barrier
rep polysac structure
SECONDARY structure
what is a lipopolysaccharide
gram -Ve outer mem
glycolipid estrutural role
antigen and bacterial toxin
what is flagella
protein unit used for motility
what is fimbriae
gram -ve
pilin no motor
more for adherence and sex
what is the cytoplasm mem
lipid bilayer retains cyto selective barrier transport reaction surface (resp, lipid synthesis)
what is protomotive effect at the cytoplasmic mem
electrons released from high energy compounds in cyto
reach mem and pass through electron acceptors
protons passed outside mem
under anaerobic conns what happens to pyretic acid
conv to lactic acid or ethanol
what is an excellent oxygen acceptor
hydrogen = water
what is distinct about prokaryotic preteen synthesis
distinct proteins
cootransC/transL
cytoplasmic mem
target for antibiotics
what is the nuceloid
contains DNA
no nuclear mem
chromo single circular mol
primitive DNA segregation machinery
how does food influence prokaryotic growth
C source organic (proteins/sugars) inorganic (CO2) O & H N source (aa, ammonia) inorganic salts (P, S, K, Mg) vitamins
how does temp influence prokaryotic growth
psycrophiles (low temp)
thermophiles (high temp)
mesophils (body temp)
what is the pH range for human commensals
6.8-7.2
what is the osmotic protection fro human commensals
0.85% NaCl
what are the types of oxygen for prokaryotic growth
aerobes, microaerophiles, facultative anaerobes, anaerobes
what is the phases of bacterial growth curve
lag phase
expo phase
stationary phase
decline phase
what is a virus
very small
non cellular microbe
obligate intracellular parasite
what is the virus particle
nucleic acid (DNA/RNA) protein shell (capsid) lipid layer too (envelope)
what is viral reproduction
unique assembly
virus genome syn virus proteins and progeny virus genome using cellular machinery
what is the development of oral flora like
pioneer orgs (s,cocci) quickly establish to pioneer microbial comm to climax
what does whole saliva compose of
secretory IgA, IgG proteins enzymes electrolytes polymorphs
what is standard infection confrtrl
same cross infection control procedures must be used for all pt’s
