M1 Revision Flashcards

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1
Q

what re the man div of living orgs

A

plants
animals
micro orgs

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2
Q

what re the man div of micro orgs

A

algae
fungi
bateria
protozoa

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3
Q

what si size related

A

complexity

how quick grow and evolve

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4
Q

how far does a spore travel in comparison to the other viruses

A

further think cough

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5
Q

what are other process need to be aware of

A

cell cycle/ prolif
evolution (resistance)
evasion
colonisation

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6
Q

what are the basic features of prokaryotic cell

A
small and simple 
primitive intrcellular strutture 
circular chromosome 
peptidoglycan cell wall 
ribosome (70s)
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7
Q

what are th basic features of a eukaryotic cell

A
large and complex 
internal memo and mem bound organs 
linear chromo
cell envelope or rigid cell wall 
ribo (80s)
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8
Q

what is the generalisation of eukaryotic structure

A

compartmentalised

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9
Q

what are some internal features of eukaryote

A
vacuoles 
chloroplast - in plant
mito
ribo
golgi
nucleolus
ER
plasma mem
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10
Q

what are some external features of eukaryotic cell

A

cell wall
capsule
cilia
flagella

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11
Q

why is prokaryotic cytoplasmic mem more imp

A

imp barrier of in and out

resp events = Photomotive force

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12
Q

what is important about cell wall

A

structural barrier
(adhesins, in/out)
chem reactions
(energy, transC, transL)

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13
Q

what do cell walls contain

A

peptidoglycan

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14
Q

what s peptidoglycan

A

sugar lattice

peptide bridges

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15
Q

what does ftsI encode

A

PBP3

penicillin binding protein

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16
Q

what is FtsI

A

transmembrane protein

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17
Q

what is transpeptidase

A

enzyme cross links peptide side chains in transpepetidation

18
Q

what is the target of penicillin

A

FtsI

19
Q

what is the cell wall like in gran -ve

A

thin cell wall located between inner and outer mem

20
Q

what is cell wall like in gam +ve

A

thick multilayer cell wall and cytoplasmic mem

21
Q

what are the cell wall basic features

A

rigid layer
barrier
rep polysac structure
SECONDARY structure

22
Q

what is a lipopolysaccharide

A

gram -Ve outer mem
glycolipid estrutural role
antigen and bacterial toxin

23
Q

what is flagella

A

protein unit used for motility

24
Q

what is fimbriae

A

gram -ve
pilin no motor
more for adherence and sex

25
Q

what is the cytoplasm mem

A
lipid bilayer 
retains cyto
selective barrier 
transport 
reaction surface (resp, lipid synthesis)
26
Q

what is protomotive effect at the cytoplasmic mem

A

electrons released from high energy compounds in cyto
reach mem and pass through electron acceptors
protons passed outside mem

27
Q

under anaerobic conns what happens to pyretic acid

A

conv to lactic acid or ethanol

28
Q

what is an excellent oxygen acceptor

A

hydrogen = water

29
Q

what is distinct about prokaryotic preteen synthesis

A

distinct proteins
cootransC/transL
cytoplasmic mem
target for antibiotics

30
Q

what is the nuceloid

A

contains DNA
no nuclear mem
chromo single circular mol
primitive DNA segregation machinery

31
Q

how does food influence prokaryotic growth

A
C source organic (proteins/sugars) inorganic (CO2)
O & H
N source (aa, ammonia)
inorganic salts (P, S, K, Mg)
vitamins
32
Q

how does temp influence prokaryotic growth

A

psycrophiles (low temp)
thermophiles (high temp)
mesophils (body temp)

33
Q

what is the pH range for human commensals

A

6.8-7.2

34
Q

what is the osmotic protection fro human commensals

A

0.85% NaCl

35
Q

what are the types of oxygen for prokaryotic growth

A

aerobes, microaerophiles, facultative anaerobes, anaerobes

36
Q

what is the phases of bacterial growth curve

A

lag phase
expo phase
stationary phase
decline phase

37
Q

what is a virus

A

very small
non cellular microbe
obligate intracellular parasite

38
Q

what is the virus particle

A
nucleic acid (DNA/RNA)
protein shell (capsid)
lipid layer too (envelope)
39
Q

what is viral reproduction

A

unique assembly

virus genome syn virus proteins and progeny virus genome using cellular machinery

40
Q

what is the development of oral flora like

A

pioneer orgs (s,cocci) quickly establish to pioneer microbial comm to climax

41
Q

what does whole saliva compose of

A
secretory IgA, IgG
proteins 
enzymes
electrolytes
polymorphs
42
Q

what is standard infection confrtrl

A

same cross infection control procedures must be used for all pt’s