M10 Gram -Ve Bacteria 1 Flashcards
what re the four main gram -ve bac
cocci
curved rods
strict anaerobes
facultative anaerobes
what are the two aerobic gram -ve cocci
neisseria
moraxella
what is an example of anaerobic gram -ve cocci
veillonella
what re some features of neisseira
gram -ve facultative aerobe non motile cocci pairs, triads, clusters
what are the pathogenic neisseria
gonorrhoeae
meningitides
what are some oral neisseria
subflava
sicca
what is imp about oral neisseria
early tooth colonisers
what is n. subflava
most commonly isolated
saccharolytic produces polysac and yellow pigment
what is n. sicca
mouth similar to subflava
no pigment prod
are n. subflave or n.sicca pathogenic
no
what is moraxella
gram -ve bac neiseira like asaccharyltic polysaccharide -ve Dnase +ve
what is the most imp sp of moraxlla
catarrhalis
what is moraxella catarrhalis
commensal
pathogen - tonislar b cells causing endocarditis, meningitis
what does catarrhalis prod
beta lactamase
complicates Ab therapy
what is veillonellla
small gram -ve anaerobic cocci
what does veillonella not do
ferment carbs
what des veillonella use as energy source
lactic acid –> acetate + 2 propionic acid + CO2 + H20
what is the most common strain of veillonell
parvula
what kind of bac is parvula
strict anaerobe
what does veillonella parvula do
catabolises lactic acid to weaker organic acids - inc pH
what bac are present in community acquired pneumonia
moxarella 9.4%
veillionela 1.6%
oral streps 9.4%
what are GNABs
gram negative anaerobic Bacilli
what re some motile GNABs
selenomas
centipeda
helicobacter
what are some non motile GNABs
bacteriodes porphyromonas prevotella (tannerella fusobac)
what is usually prescribed for anaerobic microbes
metronidazole
what are selenomonas
-crescent + flagellae
- gram -ve
assc with aggressive periodontitis
what are some imp sp of selnomonas
sputigena
noxia
what are centipeda
one sp - periodontii
- flagella all round
what are helicobacter
H.pylori
assc w/gastritis, peptic ulcers
in dental plaque
what kind of bac are bacteriodes
strictly anaerobic gram -v bacilli
what is a main sp of bacteriode
fragilis
in mouth
main pathogen
what does a healthy gingival crevice contain
Gm +ve cocci
below gingival crevice what happens
anaerobic conditions
nutrient from gingival tissues rather than food or saliva
what happens in periodontitis
plaque inc = gingivitis
(streptococcus)
plaque between tooth and gum = pocket
(actinomyces )
pocket deep, gingiva recede and bone lost
(porphyromomas gingivalis and prevotella intermedia)
what are some other sp of bactericiodes
prevotella
porphyromonas
tannerella forsythia
whatarethe common themes of the bacteriodes
asaccharolytic
dark pigment
what are some imp features of porphyromonas
dark pigment GNAB
assacharolytic - prod proteases
per pocket
p.gingivalis periodontopathogen
what are some imp features of prevotella
dark pigment
saccharolytic
(sucrose –> acetic acid and succinic acid)
what doe num of prevotella intermedia correlate with
periodontitis sererity
what is prevotella dentalis
non pigmented
from root canals and perio pocket
what does black pigmented bac require
iron
what is o surface of BPB
porphyrins
with iron but without = photosensitive
what is treat BPB with blue light
excitation
prod reactive oxygen species
destroy lipids,protein etc
