Vasodilators

Question 1

Some vasodilators are selective for ____________, some are selective for ________________ and some dilate both types of vessel

Answer 1

arterioles; veins

Question 2

Drugs that dilate arterioles can reduce cardiac __________________ and can thereby reduce cardiac work while increasing ________________ and ____________

Answer 2

cardiac output; tissue perfusion

Question 3

Drugs that dilate veins reduce cardiac ______________ and can thereby reduce

Answer 3

cardiac work, cardiac output and tissue perfusion

Question 4

Principal indications for vasodilators are

Answer 4

essential hypertension, hypertensive crisis, angina pectoris, heart failure and MI

Question 5

Drugs that dilate veins can cause _______________

Answer 5

orthostatic hypotension

Question 6

Drugs that dilate arterioles or veins can cause ________________tachycardia, which increases cardiac work and elevates blood pressure. However, this can be blunted with a _________________-

Answer 6

reflex; beta blocker

Question 7

Drugs that dilate arterioles or veins can cause _______________, which can be blunted with a

Answer 7

fluid retention; diuretic

Question 8

Hydralazine causes selective dilation of ______________

Answer 8

arterioles

Question 9

Minoxidil causes selective and profound dilation of ______________-

Answer 9

arterioles

Question 10

Minoxidil causes hypertrichosis. What is this ?

Answer 10

Excessive growth of hair

Question 11

Hydralazine can cause a syndrome that resembles SLE. What does this stand for ?

Answer 11

systemic lupus erythematosus

symptoms include muscle pain, joint pain, fever, nephritis, pericarditis and the presence of antinuclear antibodies

Question 12

Sodium nitroprusside dilates __________ and ______________

Answer 12

arterioles; veins

Question 13

Prolonged infusion of nitroprusside can result in toxic accumulation of cyanide and thiocyanate. TRUE OR FALSE

Answer 13

TRUE