ANEMIA Flashcards
a deficiency in the number of RBC , the quantity or quality of hemoglobin and/or volume of packed RBCs (hematocrit)
anemia
because RBCs transport O2, erythrocyte disorders can lead to tissue ____________
hypoxia. This accounts for many of the signs & symptoms of anemia. Anemia is a manifestation of a pathologic process
How is anemia diagnosed ?
based on a CBC, reticulocyte count, and peripheral blood smear
various types of anemia can be classified according to either _____________ or ___________
morphology (cellular characteristic) or etiology (cause)
___ levels are often used to determine the level of anemia
hemoglobin
the clinical manifestations of anemia are caused by the body’s response to
tissue hypoxia
Mild states of anemia are between __________ g/dL and can exist without causing symptoms.
10-12 Hgb g/dL.
If symptoms develop, it is because the patient has an underlying disease or is experiencing a compensatory response to heavy exercise. Symptoms include mild fatigue, palpitations, and dyspnea
Moderate anemia levels
HgB 6-10 g/dL
fatigue, palpitations, dyspnea can be experienced while resting as well as with activity
Severe anemia levels
HgB < 6
patient has many clinical manifestations involving multiple body systems
MORPHOLOGIC TYPE OF ANEMIA: normocytic, normochromic
normal size and color of RBC
can happen from acute blood loss, hemolysis, chronic kidney disease, sickle cell anemia
MORPHOLOGIC TYPE OF ANEMIA: microcytic, hypochromic
small size, pale color
can happen from iron deficiency anemia, thalassemia, lead poisoning, vitamin B6 deficiency
MORPHOLOGIC TYPE OF ANEMIA: macrocytic (Megaloblastic), normochromic
Large size, normal color
can be caused by Vitamin B12 deficiency, liver disease, and folic acid deficiency
cause of anemia: Decreased RBC production. This can occur from
decreased iron availability
decreased erythropoietin
deficient nutrients (iron, Vitamin B12, folic acid)
causes of anemia: BLOOD LOSS. this can occur from
chronic causes - liver disease, bleeding duodenal ulcer, colorectal cancer
acute causes - acute trauma, ruptured aortic aneurysm, GI bleeding
causes of Anemia: INCREASED RBC destruction. this can occur from
hemolysis - sickle cell disease, medication (Methyldopa), incompatible blood, trauma (cardiopulmonary bypass)