Vasc- pathologies and collateral circulation Flashcards
what does phlegmsia mean?
- inflammation
- used in reference to extreame cases of lower extremity DVT that cause critical limb ischemia and possible limb loss
Phlegmasia alba dolens (PAD) describes?
parient with swollen and white leg bevause of early compromise of arterial flow secondary to extensive DVT
What is milk leg? who does it mainly affect?
- milk leg is white leg associated with Phlegmasia albe dolens
- affects women in 3rd tri of pregnancy or post partum
Phlegmasia cerulea dolens is more advanced and considered a persursor for what?
frank venous gangrene
what is Phlegmasia cerulea dolens charaterized by? (3)
- severe swelling
- cyanosis
- blue discoloration of the extremity
Phlegmasia alba dolens 4 clinical presentations?
- milk leg/ white leg
- edema and discomfort
- leg pale and cool
- diminished arterial pulse due to spasm
Phlegmasia cerulen dolens clinical presentation?
- painful blue adema
- pain
- cyanosis
- irreversible ischemia
- necrosis
- gangrene
Phlegmasia cerulen dolens vs. Phlegmasia alba dolens?
cerulen- affects deep veins, superficial veins, and collaterals (more severe) (medical emergency)
alba- affects deep veins only
Phlegmasia cerulen dolens extends into capillaries in what % of cases?
40-60%
what is trousseau’s sign?
- concerns hypercoagulability associated with cancer
- based on spontaneous venous thrombosis in patients with underlying malignancy
When patients present with DVT and have no known risk factors, what is the underlying concern?
they may have an occult malignancy
T or F- DVT associated with malignancy tends to be much more extensive and aggressive than DVT in the nonmalignant setting?
true
clinical presentation of DVT in occult malignancy?
very swollen and painful extremity
Patients with DVT related to Trousseau’s syndrome usually clinically manifest cancer within how many years?
1-2 years
Malignancies associated with venous thrombosis typically arise in? (5)
- breast
- GI tract
- GU tract
- lung
- brain
SCV obstruction is difficult to diagnose due to a lack of visualization and location of clavicle so diagnosis relies on what?
- secondary signs of obstruction
- pressure fluctuation in the atrium are readily transmitted into the vein producing a pulsatile waveform
- when pulsatility is absent SVC obstruction is present
many cases of SCV thrombosis involve?
IJV thrombosis- therefore should be part of the examination
if the SVC is the site of obstruction what may occur?
- collateral flow in the internal mammary veins may occur (flow appears reversed)
What is Lemierre’s syndrome also known as?
- jugular vein thrombosis
what is lemierres syndrome?
- patient with a neck infection and enlarged lymph nodes
- IJV compression results in thrombus formation due to stasis
- bacteria from throat can spread to major blood vessels and poison blood stream leading to patient becoming septic
what is Behcet’s disease?
- inflammation in blood vessels
what does Behcet’s disease cause?
- redness
- pain
- swelling in arms and legs
Behcet’s disease in large arteries?
- inflammation that can lead to complications such as aneurysms or blockage of vessel
Behcet’s disease can affect? (7)
- mouth
- genitals
- eyes
- joints
- digestive system
- brain
What is the etiology of IVC thrombus? (3)
- mirrors that of DVT in general
- wall damage
- hypercoagulability
- venous stasis