Vancomycin

Question 1

MOA:

Answer 1

1. Prevents assembly of bacterial cell wall

Question 2

Spectrum:

Answer 2

1. Gram-positive organisms:
   Streptococcus
   Enterococcus
   MRSA
   MRSE
   Clostridium

Question 3

Indications:

Answer 3

1. MRSA infections of skin and soft tissue
2. Vascular access site infections
3. Infections in prosthetic devices
4. C. dificile colitis - administered orally
5. Gram-positive infections in patients with Hx of serious allergic reactions to beta-lactam A/Bs

Question 4

S/E:

Answer 4

1. Red man syndrome
2. Fever
3. Reversible nephrotoxicity
4. Immune thrombocytopenia