Unit 4 -Vasculature: Microcirculation, lymphatics, and Veins Flashcards

1
Q

What are the four types of capillaries?

A

Continuous capillaries, fenestrated capillaries, sinusoids (discontinuous capillaries), and lymphatic capillaries

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2
Q

What are is the most common type of capillaries?

A

continuous capillaries

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3
Q

What is the structure of continuous capillaries?

A

made up of tight junctions with no pinocytotic vesicles or clefts

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4
Q

What is the function of continuous capillaries?

A

they carry proteins for amino acids and glucose

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5
Q

Where are fenestrated capillaries located?

A

in the GI tract/intestine, kidney, and endocrine pancreas

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6
Q

Where are the fenestrations of fenestrated capillaries located?

A

in the capillary wall

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7
Q

What is the function of fenestrated capillaries?

A

they allow rapid exchange of large molecules and fluid

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8
Q

What is the structure of sinusoids?

A

they have large clefts and fenestrae and a discontinuous basal lamina layer

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9
Q

Where are sinusoid capillaries located?

A

in the liver, spleen, lymphoid organs and bone marrow

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10
Q

What is the function of sinusoid capillaries?

A

they allow rapid exchange of larger molecules, particles, whole cells, and fluid between the blood and interstitium

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11
Q

What is the structure of lymphatic capillaries?

A

the endothelium overlaps in places, there are no tight junctions, it has intercellular clefts

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12
Q

What are lymphatic capillaries supported by?

A

anchoring filaments

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13
Q

What is the function of lymphatic capillaries?

A

they pull away fluid to keep the interstitium dry so that filtration can continuously occur

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14
Q

What does bulk flow occur through?

A

capillary pores

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15
Q

What influences bulk flow?

A

hydrostatic pressure

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16
Q

What does fluid movement across the capillary membrane depend on?

A

the sum of osmotic pressure and hydrostatic pressure across the membrane

17
Q

Where is fluid filtered and where is it absorbed?

A

it is filtered at the arteriole end and absorbed at the venous end

18
Q

What is the Starling equation?

A

Kf(Pc-Pi)-(πc - πi)

19
Q

What does Pc in the starling equation stand for?

A

capillary hydrostatic pressure

20
Q

What does Pi in the starling equation stand for?

A

interstitial hydrostatic pressure

21
Q

What does πc in the starling equation stand for?

A

capillary oncotic pressure

22
Q

What does πi in the starling equation stand for?

A

interstitial oncotic pressure

23
Q

What does causes interstitial edema?

A

increase in capillary hydrostatic pressure
decrease in capillary oncotic pressure
increase in capillary permeability
decrease in lymphatic flow

24
Q

What is the function of lymphatics?

A

drain excess fluid from interstitial space, removing excess interstitial protein and returning it back into circulation, and removing particles and bacteria into the blood system

25
Q

What determines the rate of lymph flow?

A

muscle contraction, movement, and arterial pulsations

26
Q

What influences pressure in all systemic veins?

A

right arterial pressure

27
Q

What does greater venous restriction influence?

A

flow

28
Q

What is the function of veins?

A

return blood to the heart and are storage areas

29
Q

What is vascular compliance?

A

The ability of a blood vessel wall to expand and contract passively with changes in pressure is an important function of large arteries and veins.

30
Q

How is vascular compliance calculated?

A

ΔV/ΔP

31
Q

When the heart starts, what happens to the volume in veins?

A

it decreases

32
Q

How does a rapid increase in volume affect veins?

A

It increases its pressure but not drastically

33
Q

When the heart starts, what happens to volume in arteries?

A

it increases

34
Q

How does a rapid increase in volume affect the pressure in arteries?

A

It increases it dramatically