Exam 2 Lecture - Developmental Anatomy Flashcards

1
Q

What are congenital defects?

A

defects that are present at birth

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2
Q

What can cause congenital defects?

A

anything that the mother comes in contact with can affect the pregnancy; environmental, vaccines, medicines

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3
Q

What is a critical period of development?

A

a point in time when we have an organ or an organ system developing

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4
Q

When is a fetus the most susceptible to environmental influences?

A

during critical periods because they are undergoing a lot of replication

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5
Q

What can disruption in one organ system lead to?

A

can impact the development of another organ systems

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6
Q

True or False: Critical periods only occur in utero

A

False: they can occur post natally

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7
Q

What is the cause of cycloptic lamb?

A

the ewe ingests the veratrum californicum at 14-15 days of gestation that can cause this defect

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8
Q

What could cause cerebellar hypoplasia?

A

genetic reasons, infections, toxins

Specifically: bovine viral diarrhea and feline panleukopenia

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9
Q

How can bovine viral diarrhea cause cerebellar hypoplasia?

A

If the cow is infected with BVD within 100-170 days of gestation the calf could be infected which in turn will cause cerebellar hypoplasia

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10
Q

How can feline panleukopenia cause cerebellar hypoplasia?

A

If the queen gets infected with feline panleukopenia in the last part of gestation or the kitten gets infected within the first 14 days of birth the kitten can develop cerebellar hypoplasia

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11
Q

Cells in the zygote are____.
(A) restricted
(B) unrestricted

A

unrestricted

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12
Q

Why do cells become more restricted throughout development?

A

because their environment is changing and the cells that they are in contact with are changing

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13
Q

True or False: Cells have the same DNA later in development that they had in early development

A

True: although the cells are more restricted later in development, their DNA does not change

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14
Q

What is a zygote?

A

a really big cell

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15
Q

What is the zona pellucida?

A

the glycoprotein covering that surrounds the zygote

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16
Q

What is a cleavage?

A

it is where the zygote divides

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17
Q

True or False: When the cell continues to divide, and the zona pellucida is still in place, the zygote grows to make space for the new cells

A

False

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18
Q

When does the zygote become the morula?

A

when there are 16 blasomeres present

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19
Q

What do the outer blastomeres of the morula become?

A

trophoblast cells which help form part of the placenta

20
Q

What do the inner blastomeres of the morula become?

A

contribute to the inner cell mass - embryo

21
Q

What blastomeres are the target of embryonic splitting

A

the inner blastomeres

22
Q

When does the morula become the blastula?

A

when the zona pellucida has broken down and the embryo begins to grow

23
Q

What is the purpose of the blastocoele?

A

to help facilitate diffusion

24
Q

When does gastrolation normally occur?

A

around 14 days into the gestational period

25
Q

Right before gastolation, what are the structures of the embryo?

A

amniotic cavity, yolk sac, bilaminar disc (embryo)

26
Q

What is the bilaminar disc made out of?

A

epiblast cells and hypoblast cells

27
Q

What is the purpose of gastrolation?

A

to give rise to three germ layers and marks the beginning of organ and body development

28
Q

What initiates gastrolation?

A

the formation of the primitive streak and the primitive node

29
Q

What is the importance of the primitive streak aside from initiating gastrolation?

A

it gives the embryo its polarity

30
Q

What forms the endoderm?

A

the wave of epiblast cells that flow deep through the primitive groove

31
Q

What forms the mesoderm?

A

the wave of epiblast cells that flow through the primitive groove but lay closer to it than the endoderm

32
Q

What forms the ectoderm?

A

the wave of epiblast cells that do not migrate at all

33
Q

Where is the notochord formed?

A

in the mesoderm

34
Q

What does the ectoderm become?

A

skin, neural tissue, skeletal and connective tissue of the head

35
Q

What does the mesoderm become?

A

muscle, skeleton, internal organs (specifically urogenital), cardiovascular season

36
Q

What does the endoderm become?

A

the lining of the digestive and respiratory tracts as well as the organs of digestion

37
Q

What initiates the creation of the coelom?

A

small vesicles called ceolomic vesicles

38
Q

Where are coelomic vesicles located?

A

within the mesoderm

39
Q

When these vesicles coalesque, what do they form?

A

the ceolem; the somatic layer and the splanchnic layer

40
Q

What does the somatic coelem become?

A

the body wall, adjacent to the ectoderm

41
Q

How does the somatic coelem grow?

A

ventrally and medially

42
Q

What does the splanchnic coelem become?

A

organs, adjacent to the endoderm, the primitive gut tube

43
Q

How does the splanchnic coelem grow?

A

ventrally and medially

44
Q

What is schistosmomus reflexus?

A

when the body wall never forms in utero; most common in cattle

45
Q

What are the 3 situations that can result in monozygotic twinning?

A
  1. blastomeres split apart and form 2 completely separate embryos
  2. two inner cell masses develop (share the same placenta)
  3. No separation of the zygote or inner mass cells (share amniotic cavity and placenta; can lead to conjoined twins)
46
Q

What is an amorphous globosus?

A

a hairy glob of muscle and connective tissue that comes out after a calf has been born