unit 2, cell mediated immune response

Question 1

is phagocytosis specific or non specific?

Answer 1

non specific

Question 2

where are t cells made?

Answer 2

made in the bone marrow, but mature in the thymus gland

Question 3

what do t cells respond to?

Answer 3

APC cells, not antigens floating withing the blood or in body fluids

Question 4

what are antigen presenting cells?
(APCs)

Answer 4

a cell that presents non self antigens on the surface of its membrane
eg) macrogphages after performing phagocytosis, infected self cell from a virus

Question 5

what is the result of APC’s?

Answer 5

they activate T helper cells

Question 6

what do T helper cells do?

Answer 6

-they are stimulated to divide by mitosis when attatched to non self antigen
-this forms clones
- clones examples) more t helper cells, macrophages , cytotocxic t cells, b cells, memory T cell

Question 7

what do cytotoxic (killer) t cells do?

Answer 7

destroy infected or foreign cells by releasing protein, e.g, perforin which makes pores/holes in the membrane eventually causing the cytoplasm to burst due to susbstances leaving or exiting cell

Question 8

process of cell mediated respone?

Answer 8

• pathogenic antigens are presented on the membranes of white blood cells after phagocytosis. APC’s.
  -t helper cells respond first, they have receptors that are complementary to the antigens, which they attatch to
  -this stimulates t cells to divide by mitosis creating clones, they differentiate and form) more t helper cells, cytotoxic t cells, b cell, memory T cell

Question 9

what do t helper cell clones differentiate into?

Answer 9

• cytotoxic t cells
  -B cells
  -phagocytosis
  -memory T cells