Uncommon Blood Groups

Question 1

1. The antibody to this high-prevalence antigen demonstrates mixed-field agglutination that appears shiny and
   refractile under the microscope.
   a. Vel
   b. JMH
   c. Jra
   d. Sda

Answer 1

d. Sda

Question 2

2. What red blood cell treatment can be used to differentiate
   between anti-D and anti-LW?
   a. Ficin
   b. Trypsin
   c. DTT
   d. Papain

Answer 2

c. DTT

Question 3

3. Which of the following has been associated with causing
   severe immediate HTRs?
   a. Anti-JMH
   b. Anti-Lub
   c. Anti-Vel
   d. Anti-Sda

Answer 3

c. Anti-Vel

Question 4

4. Which of the following antibodies would more likely be
   found in a black patient?
   a. Anti-Cra
   b. Anti-Ata
   c. Anti-Hy
   d. All of the above

Answer 4

d. All of the above

Question 5

5. Which of the following antigens is not in a blood group
   system?
   a. Doa
   b. LKE
   c. JMH
   d. Kx

Answer 5

b. LKE

Question 6

6. A weakly reactive antibody with a titer of 128 is neutralized by plasma. Which of the following could be the
   specificity?
   a. Anti-JMH
   b. Anti-Ch
   c. Anti-Kna
   d. Anti-Kpa

Answer 6

b. Anti-Ch

Question 7

7. An antibody reacted with untreated RBCs and DTT treated RBCs but not with ficin-treated RBCs. Which
   of the following antibodies could explain this pattern of
   reactivity?
   a. Anti-JMH
   b. Anti-Yta
   c. Anti-Cra
   d. Anti-Ch

Answer 7

d. Anti-Ch

Question 8

8. The following antibodies are generally considered
   clinically insignificant because they have not been
   associated with causing increased destruction of RBCs,
   HDFN, or HTRs.
   a. Anti-Doa and anti-Coa
   b. Anti-Ge3 and anti-Wra
   c. Anti-Ch and anti-Kna
   d. Anti-Dib and anti-Yt

Answer 8

c. Anti-Ch and anti-Kna

Question 9

9. Which antigen is the receptor for Haemophilus influenza?
   a. AnWj
   b. PEL
   c. FORS
   d. Kna

Answer 9

a. AnWj

Question 10

10. Which antigen is not absent or is weakened on RBCs of
    individuals with PNH?
    a. Yta
    b. Cra
    c. CD59
    d. Coa

Answer 10

d. Coa

Question 11

11. Which of the following blood groups is carried on a
    structure that helps to maintain the RBC membrane
    integrity through interaction with protein band 4.1?
    a. Di
    b. Kn
    c. Ge
    d. Vel

Answer 11

c. Ge

Question 12

12. What is the name of the Knops system serologic null
    phenotype?
    a. Gregory
    b. Leach
    c. Helgeson
    d. McLeod

Answer 12

c. Helgeson

Question 13

13. Which antigen when absent produces a null in the
    Dombrock system?
    a. Hy
    b. Joa
    c. Dob
    d. Gya

Answer 13

d. Gya

Question 14

14. Which antigens are strongly expressed on placental
    tissue, allowing for the adsorption of antibodies?
    a. Cromer
    b. Knops
    c. Diego
    d. Vel

Answer 14

a. Cromer

Question 15

15. Which antigen was returned to the 901 series because
    there was no determined linkage to the SMIM1 gene?
    a. JMH
    b. Ata
    c. ABTI
    d. MAM

Answer 15

c. ABTI

Question 16

16. The FORS blood group system was first thought to
    be part of what system due to the addition of
    N-acetylgalactosamine (GalNAc) to the P antigen?
    a. ABO
    b. Lewis
    c. P1PK
    d. Globoside

Answer 16

a. ABO

Question 17

17. What glycophorin expresses the MN CHO collection
    antigens that are associated with altered levels of sialic
    acid (NeuNAc) or GlcNAc?
    a. GPA
    b. GPB
    c. GPC
    d. GPD

Answer 17

a. GPA

Question 18

18. What techniques can be used to remove the reactivity of
    Bg antigens?
    a. EDTA/glycine-HCL
    b. Platelet adsorption
    c. Chloroquine treatment
    d. All of the above

Answer 18

d. All of the above

Question 19

19. ABTI was thought to be classified with which antigen
    prior to it gaining system status?
    a. Jra
    b. FORS1
    c. Vel
    d. Lan

Answer 19

c. Vel

Question 20

20. The Jr(a–) phenotype is found more commonly in:
    a. Japanese.
    b. African Americans.
    c. South American Indians.
    d. Caucasians.

Answer 20

a. Japanese.