ABO blood group system

Question 1

1. An ABO type on a patient gives the following reactions:

What is the patient’s blood type?
a. O
b. A
c. B
d. AB

Answer 1

d. AB

Question 1

2. The major immunoglobulin class(es) of anti-B in a group
   A individual is (are):
   a. IgM.
   b. IgG.
   c. IgM and IgG.
   d. IgM and IgA

Answer 1

a. IgM.

Question 2

3. What are the possible ABO phenotypes of the offspring
   from the mating of a group A to a group B individual?
   a. O, A, B
   b. A, B
   c. A, B, AB
   d. O, A, B, AB

Answer 2

d. O, A, B, AB

Question 3

4. The immunodominant sugar responsible for blood group
   A specificity is:
   a. L-fucose.
   b. N-acetyl-D-galactosamine.
   c. D-galactose.
   d. Uridine diphosphate-N-acetyl-D-galactose.

Answer 3

b. N-acetyl-D-galactosamine.

Question 4

5. What ABH substance(s) would be found in the saliva of
   a group B secretor?
   a. H
   b. H and A
   c. H and B
   d. H, A, and B

Answer 4

c. H and B

Question 5

6. . An ABO type on a patient gives the following reactions:

The reactions above may be seen in a patient who is:
a. A1 with acquired B.
b. A2B with anti-A1.
c. AB with increased concentrations of protein in the
serum.
d. AB with an autoantibody.

Answer 5

b. A2B with anti-A1.

Question 6

7. Which of the following ABO blood groups contains the
   least amount of H substance?
   a. A1B
   b. A2
   c. B
   d. O

Answer 6

a. A1B

Question 7

8. You are working on a specimen in the laboratory that
   you believe to be a Bombay phenotype. Which of the following reactions would you expect to see?
   a. Patient’s cells + Ulex europaeus = no agglutination
   b. Patient’s cells + Ulex europaeus = agglutination
   c. Patient’s serum + group O donor RBCs = no agglutination
   d. Patient’s serum + A1 and B cells = no agglutination

Answer 7

a. Patient’s cells + Ulex europaeus = no agglutination

Question 8

9. An example of a technical error that can result in an
   ABO discrepancy is:
   a. Acquired B phenomenon.
   b. Missing isoagglutinins.
   c. Cell suspension that is too heavy.
   d. Acriflavine antibodies.

Answer 8

c. Cell suspension that is too heavy.

Question 9

10. An ABO type on a patient gives the following reactions:

These results are most likely due to:
a. ABO alloantibody.
b. Non-ABO alloantibody.
c. Rouleaux.
d. Cold autoantibody

Answer 9

b. Non-ABO alloantibody.