Pretransfusion testing

Question 1

1. Which is not included on a properly labeled specimen?
   a. Two unique patient identifiers
   b. Date and time of draw
   c. Phlebotomist’s initials
   d. Patient’s home address

Answer 1

d. Patient’s home address

Question 2

2. How many days before a pretransfusion specimen expires?
   a. 3 days
   b. 7 days
   c. 14 days
   d. 1 month

Answer 2

a. 3 days

Question 3

3. How many days must a pretransfusion specimen and
   donor unit segments be retained post-transfusion?
   a. 3 days
   b. 7 days
   c. 14 days
   d. 1 month

Answer 3

b. 7 days

Question 4

4. If a blood type cannot be resolved, what ABO group
   should be selected for a red blood cell transfusion?
   a. Group A
   b. Group B
   c. Group O
   d. Group AB

Answer 4

c. Group O

Question 5

5. Which antibody specificity is not required in antibody
   detection tests?
   a. K
   b. Cw
   c. Fya
   d. S

Answer 5

b. Cw

Question 6

6. A patient has a history of anti-Jka. The antibody screen is
   currently negative. Which red blood cell unit should be
   selected, and what type of crossmatch should be performed?
   a. Jk(a-) red blood cells, computer crossmatch
   b. Jk(a-) red blood cells, antiglobulin crossmatch
   c. Jk(a-) red blood cells, immediate spin crossmatch
   d. ABO-compatible because the antibody screen is
   negative

Answer 6

b. Jk(a-) red blood cells, antiglobulin crossmatch

Question 7

7. Which is not true of rouleaux formation?
   a. Mimics agglutination
   b. Appears like a “stacking of coins”
   c. Can be seen in the antiglobulin test
   d. Can be dispersed by saline

Answer 7

c. Can be seen in the antiglobulin test

Question 8

8. A patient’s blood type is AB-negative, but there are no
   AB-negative red blood cell units available. What donor
   units could be selected?
   a. A-negative
   b. O-positive
   c. B-positive
   d. All of the above

Answer 8

a. A-negative

Question 9

9. A patient requires 15 units of thawed plasma for
   an apheresis procedure. The patient’s blood type is
   O-negative. What donor units could be selected?
   a. O-negative
   b. AB-positive
   c. A-negative
   d. All of the above

Answer 9

d. All of the above

Question 10

10. The American College of Surgeons recommends transfusion of red blood cells, thawed plasma, and platelets
    in what ratio for a massive transfusion?
    a. 2 units of red blood cells for every unit of platelets
    b. 1 unit of red blood cells to 1 unit of thawed plasma
    to 1 unit of platelets
    c. 1 unit of red blood cells to 3 units of thawed plasma
    d. It’s an emergency. Give the surgeon whatever she
    wants

Answer 10

b. 1 unit of red blood cells to 1 unit of thawed plasma
to 1 unit of platelets

Question 11

11. A patient’s antibody screen was positive and an anti-c
    was identified. Antiglobulin crossmatches were performed with c-negative units and 1 of the 6 units was
    incompatible. What should be performed to resolve the
    incompatible crossmatch?
    a. Give O-negative red blood cells
    b. Retype the incompatible unit for the c antigen
    c. Perform a DAT on the incompatible unit
    d. Perform additional identification testing to include
    low-specificity antigens
    e. b, c, and d

Answer 11

e. b, c, and d

Question 12

12. A mother, 30 weeks’ pregnant, has anti-K with a titer of 32.
    An intrauterine red blood cell transfusion is indicated. The
    donor unit selected should be all of the following except:
    a. O-negative
    b. K-negative
    c. Positive for sickling hemoglobin
    d. Irradiated

Answer 12

c. Positive for sickling hemoglobin

Question 13

13. A patient with sickle cell disease is B-positive with a positive antibody screen. The antibody identified is anti-D,
    and the autocontrol is negative. What is a possible
    explanation?
    a. The patient is weak D-positive
    b. Autoantibody is present
    c. Patient possesses the partial D phenotype
    d. The patient has a positive DAT

Answer 13

c. Patient possesses the partial D phenotype