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***Modern blood banking & Transfusion Practices > Fundamentals of Immunology > Flashcards

Fundamentals of Immunology Flashcards

1
Q
  1. Which of the following is not involved in the acquired
    (adaptive) immune response?
    a. Phagocytosis
    b. Production of antibody or complement
    c. Induction of immunologic memory
    d. Accelerated immune response upon subsequent
    exposure to antigen
A

a. Phagocytosis

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2
Q
  1. Which cells are involved in the production of antibodies?
    a. Dendritic cells
    b. T lymphocytes
    c. B lymphocytes
    d. Macrophages
A

c. B lymphocytes

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3
Q
  1. Which of the following cells is involved in antigen recognition following phagocytosis?
    a. B lymphocytes
    b. T lymphocytes
    c. Macrophages
    d. Granulocytes
A

b. T lymphocytes

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4
Q
  1. The role of the macrophage during an antibody response
    is to:
    a. Make antibody.
    b. Lyse virus-infected target cells.
    c. Activate cytotoxic T cells.
    d. Process antigen and present it.
A

d. Process antigen and present it.

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5
Q
  1. Which of the following immunoglobulins is produced in
    the primary immune response?
    a. IgA
    b. IgE
    c. IgG
    d. IgM
A

d. IgM

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6
Q
  1. Which of the following immunoglobulins is produced in
    the secondary immune response?
    a. IgA
    b. IgE
    c. IgG
    d. IgM
A

c. IgG

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7
Q
  1. Which of the following MHC classes encodes complement components?
    a. Class I
    b. Class II
    c. Class III
    d. Class IV
A

b. Class II

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8
Q
  1. Which of the following immunoglobulins is most efficient
    at binding complement?
    a. IgA
    b. IgE
    c. IgG
    d. IgM
A

d. IgM

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9
Q
  1. Which portion of the immunoglobulin molecules contains complement binding sites?
    a. Heavy chain variable region
    b. Light chain variable region
    c. Heavy chain constant region
    d. Light chain constant region
A

c. Heavy chain constant region

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10
Q
  1. Which complement pathway is activated by the formation of antigen-antibody complexes?
    a. Classical
    b. Alternative
    c. Lectin
    d. Retro
A

a. Classical

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11
Q
  1. Which of the following is known as the “recognition
    unit” in the classical complement pathway?
    a. C1q
    b. C3a
    c. C4
    d. C5
A

a. C1q

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12
Q
  1. Which of the following is known as the “membrane
    attack complex” in the classical complement pathway?
    a. C1
    b. C3
    c. C4, C2, C3
    d. C5b, C6, C7, C8, C9
A

d. C5b, C6, C7, C8, C9

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13
Q
  1. Which of the following immunoglobulin classes is
    capable of crossing the placenta and causing hemolytic
    disease of the newborn?
    a. IgA
    b. IgE
    c. IgG
    d. IgM
A

c. IgG

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14
Q
  1. Which of the following refers to the effect of an excess
    amount of antigen present in a test system?
    a. Postzone
    b. Prozone
    c. Zone of equivalence
    d. Endzone
A

a. Postzone

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15
Q
  1. Which of the following refers to the presence of an
    excess amount of antibody present in a test system?
    a. Postzone
    b. Prozone
    c. Zone of equivalence
    d. Endzone
A

b. Prozone

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16
Q
  1. Which one of the following properties of antibodies is
    NOT dependent on the structure of the heavy chain
    constant region?
    a. Ability to cross the placenta
    b. Isotype (class)
    c. Ability to fix complement
    d. Affinity for antigen
A

d. Affinity for antigen

17
Q
  1. Molecules that promote the update of bacteria for
    phagocytosis are:
    a. Opsonins.
    b. Cytokines.
    c. Haptens.
    d. Isotypes
A

a. Opsonins.

18
Q
  1. Select the term that describes the unique confirmation
    of the antigen that allows recognition by a corresponding antibody.
    a. Immunogen
    b. Epitope
    c. Avidity
A

b. Epitope

19
Q
  1. Which of the following terms refers to the net negative
    charge surrounding red blood cells?
    a. Dielectric constant
    b. Van der Waals forces
    c. Hydrogen bonding
    d. Zeta potential
A

d. Zeta potential

***Modern blood banking & Transfusion Practices (29 decks)

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