Ultrafiltration Flashcards

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1
Q

Describe the structure of the glomerls

A
  • supplied with blood by a relatively wide afferent arteriole
  • the blood leaves through a narrower efferent
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2
Q

Why is the glomerulus shaped like this?

A
  • results in considerable pressure in the capillaries of the glomerulus
  • this forces blood out through capillary walls - it acts rather like a sieve
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3
Q

Where does the fluid pass after passing through the walls of the glomerulus

A
  • through the basement membrane
  • made up of a network of collagen fibres and other proteins that make up a second sieve
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4
Q

What can pass through the basement membrane?

A
  • most of the plasma contetns can pass through
  • but blood cells and many proteins are reained in the capillary because of their size
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5
Q

WHat is in the wall of the Bowman’s capsule?

A

involves special cells called podocytes

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6
Q

WHat is the function of the podocytes?

A
  • have extensions called pedicels that wrap around the capillaries
  • forms slits that make sure any cells, platelets, or large plasma protein that have managed to get through the epithelial cells and the basment cells do not get through into the tubule itself
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7
Q

What is in the filtrate that enters the capsule?

A
  • glucose
  • salt
  • urea
  • amino acids
  • water

same conc as blood

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8
Q

What is the glomerular filtration rate?

A

the volume of blood that is filtered through the kidneys in a given time

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