Respiratory substrates Flashcards

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1
Q

What is a respiratory substrate?

A
  • organic molecules broken down to release energy for synthesis of ATP
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2
Q

How does glycerol act as a respiratory substrate?

A
  • converted to pyruvate before undergoing oxidative decarboxylation, producing an acetyl group that is picked up by CoA
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3
Q

How do fatty acids in a triglyceride act as respiratory substrate?

A
  • lead to formation as many as 50 acetyl group
  • resulting in synthesis of up to 500 ATP molc
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4
Q

How do different respiratory substrate compare in terms of energy release gram for gram?

A
  • lips most
  • glycerol
  • carbs
  • proteins rougly equivalent to carbs
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5
Q

How do proteins act as respiratiory substrates?

A
  • hydrolysed to amino acids
  • then they are deaminated before they enter the respiratory pathway (usually pyruvate)
  • this requires ATP, reducing the net production
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6
Q

What is the repiratory quotient?

A
  • calculated by dividing the volume of carbon dioxide released by the volum of oxygen taken in during respiration
  • measured using respirometer
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7
Q

Why do lipids result in the production of more ATP?

A
  • contain greater proportion of C-H bonds
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8
Q

WHat are the RQ values for common respiratory substrates

A
  • carb - 1
  • protein .9
  • lipids .7
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9
Q

Why do lipids have a low RQ value?

A
  • require more oxygen to break them down and release relatively less carbon dioxide
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10
Q

What is normal value for RQ?

A
  • .8
  • showing some lipids and carbs used (and probably proteins)
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11
Q

what does a RQ value above one show?

A

anearobic respiration is occuring

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