Tumour Nomenclature and Introduction Flashcards
Neoplasia
Uncontrolled, abnormal growth of cells or tissues in the body
- Abnormal Mass of Tissue growing at rate exceeding normal tissue
- Persists in excessive manner after cessation of stimulus which evokes change
Racial Differences across gender of cancer incidence
Males - Blacks & Whites have higher incidences than asians
Females - Whites have higher incidences than asians and blacks
Surivival Rate of Breast Cancer
80%
Survival Rate of Lung Cancer
5%
Anaplasia
Loss of cell differentiation
Dysplasia
Presence of abnormal cells within tissue that is not cancerous but may become cancer
They regress after a stimulus is lost
Hyperplasia vs Neoplasia
Hyperplasia grows when exposed to stimulus but will digress when stimulus is removed
Neoplasia continues after loss of stimulus
Hallmarks of cancer
Importance of differentiation in cancer
Failure to achieve cellular differential is a feature of malignant neoplasms, allows prediction of a tumour’s likely behaviour
Differentiation of a tumour
Used to describe difference in appearance between cells of a tumour and the cell types they are derived from
Well differentiated tumours have a better prognosis
Be vaguely aware
Also be vaguely aware
Compare: Well Differentiated Tumours, Poorly Differentiated Tumours, Undifferentiated/Anaplastic Tumours
Well differentiated tumour: Composed of cells which very closely resemble the cell of origin
Poorly differentiated tumour: Composed of cells which bear little resemblance to the cell of origin, but just enough to enable the original cell type to be identified
Anaplastic tumour: Composed of cells which are so undifferentiated that their cell of origin is unknown
Discuss Breast Cancer Progression