Tumour classing Flashcards
A 45-year-old male patient is found to have a mass in the colon during a routine screening. Define the term “neoplasm” and discuss the key characteristics associated with this lesion.
lesion resulting from autonomous and abnormal growth of cells which persist after initla stimulus is removed
what is a viscus
an organ in chest of abdomen
Clinical Exam Question:
A 52-year-old female presents with a suspicious mass in her breast. A biopsy reveals the presence of neoplastic cells. In the context of this diagnosis, differentiate between neoplastic cells and stroma. Provide three distinguishing features for each, and discuss their significance in the context of cancer pathology.
Neoplastic cells
* derrived from nucleated cells
* usually monocolonal
* growth patternand synthetic activity
Stroma
* CT framework
* mechanical support and nutrion
A 45-year-old patient presents to the clinic with a painless lump in the subcutaneous tissue of the upper arm. Upon examination, the physician notes a well-defined, firm mass measuring 2 mm in diameter. The patient reports that the lump has been present for several months but has recently started to grow rapidly. The initial biopsy reveals a neoplasm, and further investigations confirm that the tumor has reached a size of 2 mm by obtaining oxygen and nutrients through diffusion alone.
What factors contribute to the further growth of the neoplasm beyond 2 mm in diameter, considering its initial reliance on diffusion for oxygen and nutrient supply?
Creating a blood supply by releasein many growth factors to create growth of a vessel in the neoplasm
what type of tumour tends to ouggrow its blood supply and cause central necrosis of the tumour
malignant
what are the characteristics of a benign neoplasm
- localised and non invasive
- slow mitotic growth
- close resemberlance of notmal tossue
- circumscibed or encapsulated
What are the characteristics of a malignant neoplasm
- poorly defined borders
- variable resemblance to origional tissue
- rapid growth
- invasive
- metastiseses
what is the suffix of cancers
-oma
Describe what an adenoma is in relation to neoplasm nomenclature
- benign
- from glandular epithlium (doesnt matter preneting gladular pattern or not)
- and also in some cases from non glandual epithelium BUT presenting glandular pattern
Describe what an papilloma is in relation to neoplasm nomenclature
- beningn
- derived from stratified squamous epithelium and urothelium
- preset in macro/micro finger like projections
*
what is a benign tumour of smooth mucle called
leiomyoma
what is a benign tumour of skeletal mucle called
Rhabodomyoma
what is a benign tumour of cartliage called
chondroma
what is a benign tumour of fibrous tissue called
fibroma
malignant tumours arising from solid mesenchymal tissues are called
sarcoma