Treating nicotine dependence

Question 1

definition: cigarette

Answer 1

any roll of tobacco wrapped in paper or any substance not containing tobacco

Question 2

how many mg of nicotine per cigarette?

Answer 2

1 mg

Question 3

how many mg nicotine per cigar?

Answer 3

100-444 mg

Question 4

what is the oral cancer and mortality risk for pipe?

Answer 4

2-3.5x higher

Question 5

what is the mechanism of action for buproprion?

Answer 5

increased dopamine in reward center mimics nicotine, may act as nicotine receptor blocker

Question 6

what is the mechanism of action for verenicline?

Answer 6

chantix binds to receptor - no reward, no craving

Question 7

what are the treatments for spit tobacco?

Answer 7

gum, patch, lozenge

Question 8

what are the best treatments for spit tobacco?

Answer 8

chantix

Question 9

smoking induces what enzyme?

Answer 9

cyp1A2 (cyp450)

Question 10

what is the effect of tobacco cessation on haloperidol?

Answer 10

increased clearance

Question 11

which affects coumadin metabolism more - smoking or spit tobacco?

Answer 11

spit tobacco

Question 12

how long can it take for coumadin to regulate as a patient goes through tobacco cessation?

Answer 12

2.5 months