Diabetes and nutrition Flashcards
definition: diabetes
a group of metabolic disorders characterized by hyperglycemia, resulting from defects in insulin secretion, insulin action, or both
what are the short term complications of diabetes?
keto-acidosis, hyperosmolality, lactic acidosis
insulin increases which processes?
- glucose uptake in muscle and adipose
- amino acid uptake and protein synthesis
- FA synthesis and esterification
- glycogen synthesis
- glycolysis
insulin decreases which processes?
- blood glucose levels
- gluconeogensis
- lipolysis
- proteolysis
how does leptin affect insulin?
suppression
how does sympathetic nervous system affect insulin?
suppression
glucagon increases what processes?
- breakdown of glycogen
- lipolysis
- gluconeogenesis
- ketogenesis
glucagon decreases what processes?
- synthesis of glycolytic enzymes
- rate of glycolysis
- glycogen synthesis
what is the effect of low blood glucose on glucagon?
stimulation
what is the effect of increased circulating amino acids on glucagon?
stimulation
what is the effect of sympathetic nervous system (eg norepi) on glucagon?
stimulation
what is the effect of hyperglycemia on glucagon?
repression
what is the effect of increased circulating fatty acids on glucagon?
repression
what is the effect of somatostatin on glucagon?
repression
definition: glycemic index
a measure of how quickly a food causes our blood sugar levels to rise (0-100)
definition: glycemic load
(glycemic index x carb content in serving) / 100
what is the best way to achieve glycemic control?
total carb intake regulation
what are the elements of metabolic syndrome?
- high TGs
- hypertension
- central obesity
- low HDL
- hyperglycemia
what is the role of viscous fiber?
blood sugar control, slows glucose absorption
what is the role of gum and pectin fiber?
forms gel with water
what is the role of incompletely fermented fiber?
enhance digestion
what is the role of cellulose and hemicellulose fiber?
substrate for microbial fermentation, helps add bulk to stool
what is the role of lignin fiber?
binds to bile acids to prevent reabsorption in the intestine
carbs should be what % of total calories in diabetic patients?
45-65%