Tranquilizers + Opioids

Question 1

Diazepam, Midazolam, Clonazepam, Lorazepam, Zolazepam/ Tiletamine
Three “categories” that these are all considered to be a part of

Answer 1

1. Tranquilizers
2. Benzodiazepine
3. Antianxiety

Question 2

The benzodiazepine tranquilizers mechanism/ action

Answer 2

Stimulate GABA

Question 3

Benzodiazepine tranquilizers have no _______________ effect and are reversable with _________________

Answer 3

Analgesic
Flumazenil

Question 4

Opioid analgesics result in a state called ______________

Answer 4

Narcosis

Question 5

Narcosis, a state induced by opioid analgesics is characterized by 4

Answer 5

1. CNS depression
2. Sedation
3. Antianxiety
4. Animal remains responsive (no
   anesthesia)

Question 6

Opioid analgesics interfere with what 3 CNS regulatory centers

Answer 6

1. Temperature (panting)
2. Respiratory (depression)
3. Parasympathetic (GI + CV)

Question 7

Analgesics can have what three types of actions on their receptors

Answer 7

1. Agonist
2. Antagonist
3. Mixed

Question 8

Five types of opioid receptors

Answer 8

1. Mu (u)
2. Kappa (k)
3. Delta (&)
4. Sigma (o)
5. ORL- 1 (orphan receptor)

Question 9

What four effects do Mu receptors produce (read)

Answer 9

1. Respiratory depression
2. Euphoria
3. Analgesic
4. Dependence

Question 10

What effects do Kappa receptors produce

Answer 10

1. Sedation
2. Spinal analgesia
3. Meiosis